Results 91 to 100 of about 93,979 (223)
Diethyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2,2-dicarboxylate
Acta Crystallographica Section E, 2010 The title compound, C18H22N2O7, was synthesized by the 1,3-dipolar cycloaddition reaction of but-3-en-2-one, diethyl 2-aminomalonate and 2-nitrobenzaldehyde. In the molecule, the pyrrolidine ring possesses an envelope conformation.
Long He
doaj +1 more source
Angewandte Chemie International Edition, Volume 65, Issue 36, 1 September 2026.Tetrazoles are reframed as substitution‐programmable heterocycles rather than static functional groups in polymer chemistry. By linking electronic identity to synthetic strategy and polymer architecture, this mini‐review establishes a design framework for translating tetrazole duality into predictable macromolecular function.
Meryem S. Akdemir, Hatice Mutlu
wiley +1 more source
Antibody-Catalysis of a Bimolecular Asymmetric 1,3-Dipolar Cycloaddition Reaction
, 2016 Antibody-Catalysis of a Bimolecular Asymmetric 1,3-Dipolar Cycloaddition ...
Yunfeng Hu (2255629) +4 more
core +1 more source
Highly Enantioselective Catalytic 1,3-Dipolar Cycloaddition Involving 2,3-Allenoate Dipolarophiles
, 2016 A bisphosphoric acid-catalyzed 1,3-dipolar cycloaddition of buta-2,3-dienoates with azomethine ylides yields 3-methylenepyrrolidine derivatives with excellent enantioselectivity (up to 97% ee)
Long He (1696168) +5 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2012 A rapid and simple procedure was devised for the synthesis of multifunctionalized cyclic β-amino esters and γ-amino alcohols via the 1,3-dipolar cycloaddition of nitrile oxides to β-aminocyclopentenecarboxylates.
Melinda Nonn +3 more
doaj +1 more source
ChemistryEurope, Volume 4, Issue 9, September 2026.A broadly applicable synthetic platform based on a DOS/LOS‐like strategy is implemented for the case of sp3‐enriched isoxazole/isoxazoline building blocks. The method is based on a [3+2] cycloaddition of nitroalkanes and various alkenes or alkynes. The utility of the proposed approach is illustrated by the discovery of JAK2‐selective inhibitors.
Bohdan A. Chalyk +12 more
wiley +1 more source
Aspects of the chemistry of some highly crowded aromatic ligands [PDF]
, 1990 A series of ortho-substituted arylchlorophosphoranes has been prepared. The structures of these compounds have been studied by the use of (^31)Cl n.q.r. and solid-state (^31)P n.m.r. . It has been shown that ortho substitution by groups such as CH(_3) or
Straw, T. A.
core
Chemistry – A European Journal, Volume 32, Issue 33, 1 September 2026.A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz +6 more
wiley +1 more source
Cyclic Thiosulfinates: Synthesis and Applications in Chemical Biology and Materials Science
ChemBioChem, Volume 27, Issue 16, 27 August 2026.Cyclic thiosulfinates (CTs) are strained organosulfur heterocyclic compounds with a polarized ─S(═O)─S─ bond that enables selective thiol reactivity. Advances in synthesis afford tunable scaffolds that support efficient proximal thiol cross‐linking and enable applications in chemical biology and materials science. Cyclic thiosulfinates (CTs) constitute
Benjamin Liebson +3 more
wiley +1 more source
ChemSusChem, Volume 19, Issue 16, 27 August 2026.A sustainable CaCO3‐supported copper catalyst, prepared by simple adsorption of Cu(II) onto natural and marble waste‐derived carbonate materials, promotes ultrasound‐assisted CuAAC reaction in water. The work provides straightforward access to 1,4‐disubstituted 1,2,3‐triazoles under mild conditions while combining catalyst recyclability with the ...
Riccardo Serra +8 more
wiley +1 more source