Diquinothiazines - Open Access .click

Results 11 to 20 of about 44 (28)

Curcuminoid Compounds Inhibit Macrophage Migration Inhibitory Factor: In Silico Study for Their Association to Anti-diabetic Potency [PDF]

—Diabetes mellitus is a health problem characterized by chronic inflammation causing complications in the cardiovascular, kidneys, eyes, and nervous system, with macrophage migration inhibitory factor (MIF) protein playing a crucial function in the ...
de Jesus, Graciana Alves, Go, Tjie Kok
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Synthesis, Characterization and Biological Evaluation of Novel 1-(3- chloro-2-Oxo-4-Phenylazetidin-1-Yl)-3-(2-Oxo-2-(10h-Phenothiazin-10- Yl)Ethyl)Urea and Thiourea Derivatives. [PDF]

, 2012
The present works discus to Phenothiazine and its derivatives reported to possess antipsychotic, antiemetic, antihistamine, antiinflammatory, anthelmintic, antitubercular, antimicrobial, antitumour, antiparkinsonism and anticancer agents.
Sheeja Devi, K
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Investigating the anti-cancer activity of novel phenothiazines in glioblastoma [PDF]

, 2018
Philosophiae Doctor - PhDGlioblastoma multiforme (GBM) remains the most malignant of all primary adult brain tumours. It is a highly invasive and vascularized neoplasm with limited treatment options and very low survival rate.
Omoruyi, Sylvester Ifeanyi
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In vitro study of antioxidant, antigylycation, sugar hydrolysis enzyme inhibitory effect and molecular in silico docking study of angularly condensed diquinothiazines

Journal of Molecular Structure
Angularly condensed diquinothiazines (MY1, MY2, and MY3) a phenothiazine derivative was evaluated for antioxidant, antiglycation, sugar hydrolysis enzyme inhibitory effect and molecular in silico docking. Antioxidants were evaluated using DPPH, chelating ion, FRAP and lipid peroxidation. Alpha glucosidase and alpha amylase inhibition was used for sugar
Małgorzata Jeleń +10 more
openaire +1 more source

Evaluation of angularly condensed diquinothiazines as potential anticancer agents

, 2020
© 2019 We present efficient synthesis of isomeric types of angularly fused diquinothiazines in the reactions of 2,2′-dichloro-3,3′-diquinolinyl disulfide and diquinodithiin with 3-, 5-, 6- and 8-aminoquinolines.
Jeleń M. +5 more
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Análise da qualidade da água e identificação de contaminantes emergentes no estuário do Rio Paraíba-PB [PDF]

Water is an essential resource with significant economic, social, and environmental value. The global increase in freshwater consumption, driven by population growth and economic development, negatively impacts its quality.
Ramalho, Raissa Tavares Estevam
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Tri- and Pentacyclic Azaphenothiazine as Pro-Apoptotic Agents in Lung Carcinoma with a Protective Potential to Healthy Cell Lines. [PDF]