Results 151 to 160 of about 16,333 (257)

Stereodivergent C‐(Hetero)Aryl Glycosylation by Nickel‐Catalyzed Redox‐Neutral Cross‐Coupling of Glycosyl Sulfonyl Hydrazides

open access: yesAngewandte Chemie, EarlyView.
A nickel‐catalyzed C–C cross‐coupling protocol employing bench‐stable glycosyl sulfonyl hydrazides as practical glycosyl radical precursors is reported. A variety of (hetero)aryl iodides underwent cross‐coupling under redox‐neutral conditions to afford structurally diverse unprotected C‐(hetero)aryl glycosides.
Cai‐Ming Wang   +3 more
wiley   +2 more sources

A Comprehensive 19F NMR Framework for Fragment‐Based Drug Discovery: The Validated Screening Library OpenFL600 and Efficient Affinity Ranking by CSAR

open access: yesAngewandte Chemie, EarlyView.
NMR screening is a powerful method for hit detection in drug‐discovery. We designed and validated the OpenFL600 19F$^{19}{\rm F}$ NMR library to probe diverse targets, including RNA, GPCRs, kinases, and proteases. This library yields target‐specific ligands without generating promiscuous binders.
Simon H. Rüdisser   +16 more
wiley   +2 more sources

Longitudinal Changes in Lipid Profile After Sustained Virological Response in Patients with Chronic Hepatitis C Treated with Direct-Acting Antivirals. [PDF]

open access: yesHealthcare (Basel)
Koppandi O   +9 more
europepmc   +1 more source

2025 KASL clinical practice guidelines for management of hepatitis C [PDF]

open access: yesClinical and Molecular Hepatology
Eun Sun Jang   +11 more
doaj   +1 more source

Real-Life Experience of Hepatitis C Treatment with Direct-Acting Antivirals in Genotypes 2 and 3. [PDF]

open access: yesTurk J Gastroenterol
Kaya SY   +17 more
europepmc   +1 more source

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