Results 161 to 170 of about 29,806 (309)

Influenza in today: direct-acting antiviral therapy

Медицинский совет, 2015
Influenza is an acute infectious disease caused by influenza virus (Orthomyxoviridae family) which affects up to 15% of the world population in the cold season. The relevance of the disease is reflected in the statistics: every year, up to 500 million people get sick with influenza globally, of which 2 million cases are fatal.
openaire   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Direct-Acting Antivirals Are a Milestone for Hepatitis C Virus Infection? Analysis of 15 Years of Patient and Diagnosis Data from a Region in Türkiye. [PDF]

J Clin Med
Yakupogullari Y, Tanrıverdi ES, Otlu B.
europepmc   +1 more source

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source

Direct-acting antivirals for chronic hepatitis C infection: a protocol for a systematic review of observational studies. [PDF]

Syst Rev
Kumburegama BWMB, Kristensen AT, Bjelakovic G, Nikolova D, Asante MA, Bjelakovic M, Koretz RL, Balakumar MM, Michelsen ME, Klingenberg SL, Gluud C.   +10 more
europepmc   +1 more source

Clinical relevance of detectable HCV RNA in the context of direct acting antivirals. [PDF]

, 2012
Crosbie, Orla, Fanning, Liam J., Hegarty, Kevin G., Kenny-Walsh, Elizabeth, Levis, John, O'Sullivan, Kathleen   +5 more
core   +1 more source

Repurposing Hepatitis C Direct-Acting Antivirals Against COVID-19

Journal of Clinical and Experimental Hepatology, 2021
Kumar, Pramod, Kulkarni, Anand, Sharma, Mithun, Rao, Padaki N.   +3 more
openaire   +3 more sources

Chronic Hepatitis C in the Direct-Acting Antivirals Era: Carcinogenesis and Clinical Implications. [PDF]

Diseases
Aydin Y, Kurt R, Tahan V, Daglilar E.
europepmc   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Hepatitis C treatment in a jail setting: A retrospective cohort analysis of low-barrier initiation of direct acting antivirals. [PDF]

Int J Drug Policy
Berk J, Akiyama MJ, Schachman N, Junkin R, Bhowmik A, Davis D, Williams S, Rich J, Murphy M.   +8 more
europepmc   +1 more source