Results 161 to 170 of about 17,033 (261)

Cerebrospinal Fluid Cytokine Expression and Relationships With Neurological Measures in Virologically Controlled People With HIV

Annals of Neurology, EarlyView.
Objective Quantify cytokines in cerebrospinal fluid (CSF) of virologically suppressed people with HIV (PWH) and people without HIV (PWoH) and correlate these with neuroimaging, neuropsychometric (NP), and neurodegenerative measurements. Methods CSF samples were collected from virologically suppressed PWH and demographically matched PWoH under a natural
Jack Peterson, Clarissa Xia, Govind Nair, Joseph Snow, Julia Stone, Gina Norato, Brandon Do, Samuel Darko, Kory Johnson, Swati Shah, Amanda Wiebold, Melina Jones, Avindra Nath, Darshan Pandya   +13 more
wiley   +1 more source

dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins

Angewandte Chemie, EarlyView.
Double‐stranded RNA (dsRNA) plays an important role in the innate immune system, but can be misregulated in disease, leading to inflammation. Despite the importance of this motif, methods for detecting dsRNA remain limited. This work shows that ADAR3 can be repurposed to provide improved detection of dsRNA, which is demonstrated in the context of viral
Weina Cheng, Tyson D. Todd, Alexandria L. Quillin, Harshad Ingle, Angela M. Halstead, Megan T. Baldridge, José B. Sáenz, Jennifer M. Heemstra   +7 more
wiley   +2 more sources

Evolution of Liver Fibrosis in Romanian HCV Patients Following Treatment with Direct-Acting Antivirals. [PDF]

J Clin Med
Balta AAS, Uibariu Barbu RE, Baroiu L, Bulza V, Bujoreanu F, Moroianu M, Ignat MD, Cambrea SC, Dumea E, Stoian V.   +9 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Hepatitis C treatment in a jail setting: A retrospective cohort analysis of low-barrier initiation of direct acting antivirals. [PDF]

Int J Drug Policy
Berk J, Akiyama MJ, Schachman N, Junkin R, Bhowmik A, Davis D, Williams S, Rich J, Murphy M.   +8 more
europepmc   +1 more source

Assessment of GALAD score as a diagnostic and prognostic factor of <i>de novo</i> hepatitis C-related hepatocellular carcinoma post treatment with direct-acting antivirals. [PDF]

Hepatol Forum
Ramadan A, Abdelaziz AO, Nabeel MM, Atef M, Kamel MH, Elbaz TM, Hatem A, Medhat E, Abdelmaksoud AH, Lithy R, Maher R, Mohamed SA, Kamel AH, Shousha HI.   +13 more
europepmc   +1 more source

Trends in Use of Direct-Acting Antivirals for Treatment of Hepatitis C Virus Infection in Australia 2016-2024. [PDF]

J Viral Hepat
Luong CL, Ellett LK, Pratt N, Staff K, Janetzki J.   +4 more
europepmc   +1 more source

Generic <i>vs</i> brand forms of direct acting antivirals for hepatitis C virus treatment in Egyptian children. [PDF]

World J Hepatol
Mogahed E, Ghita H, Enayet A, Yasin N, El-Karaksy H.   +4 more
europepmc   +1 more source

Hepatitis C Direct-Acting Antivirals in the Immunosuppressed Host: Mechanisms, Interactions, and Clinical Outcomes. [PDF]

Viruses
AlKaabi H, AlSinani S, El-Kassas M, Alswat KA, AlNaamani KM.   +4 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source