Results 21 to 30 of about 678,742 (284)

CTC-based Compression for Direct Speech Translation [PDF]

Proceedings of the 16th Conference of the European Chapter of the Association for Computational Linguistics: Main Volume, 2021
Previous studies demonstrated that a dynamic phone-informed compression of the input audio is beneficial for speech translation (ST). However, they required a dedicated model for phone recognition and did not test this solution for direct ST, in which a single model translates the input audio into the target language without intermediate ...
Gaido M., Cettolo M., Negri M., Turchi M.   +3 more
openaire   +3 more sources

Combining Co-Amorphous-Based Spray Drying with Inert Carriers to Achieve Improved Bioavailability and Excellent Downstream Manufacturability

Pharmaceutics, 2020
It is crucial to improve poorly water-soluble orally administered drugs through both preclinical and therapeutic drug discovery. A co-amorphous formulation consisting of two low molecular weight (MW) molecules offers a solubility/dissolubility advantage ...
Yingxi Zhang, Yuan Gao, Xiaoxiao Du, Rou Guan, Zhonggui He, Hongzhuo Liu   +5 more
doaj   +1 more source

Development of the technology of tablets on the basis of ademetionine 1,4-butanedisulfonate

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
During medicinal product development a lot of key points should be taken into consideration. The purpose of pharmaceutical development is not only the creation of effective and safe preparation but also the organization of appropriate conditions for the ...
K. S. Burdak, T. G. Yarnyh, M. I. Borshchevska   +2 more
doaj   +1 more source

The redesign of amoxicillin capsules as a tablet dosage form using direct compression

Libyan International Medical University Journal, 2019
Introduction: Solid dosage forms are the most commonly used dosage form for drug delivery, and tablets are more popular than capsules because of its lower production cost, minimal potential of content tampering, and the large number of designs of tablets
Salem Elgahmi, Nawal Alrishei, Rabeaa Algaraboly, Aisha Altrablesy, Idris El-Mahdi   +4 more
doaj   +1 more source

Physicomechanical Behaviour of Novel Directly Compressible Starch-MCC-Povidone Composites and their Application in Ascorbic Acid Tablet Formulation

British Journal of Pharmacy, 2018
The goal of this research was to provide critical evaluation of the physicomechanical performance of Starch-MCC-Povidone (SMP) composites engineered via co-processing strategy.
Ilyasu Salim, Olowosulu Adeniji Kehinde
doaj   +1 more source

Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone’s Particle Size on Sustained Release

Pharmaceutics, 2020
Hydrophilic matrix tablets are a type of sustained release dosage form characterized by distributing a drug in a matrix that is usually polymeric. Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase.
Anna Nardi-Ricart, Isaac Nofrerias-Roig, Marc Suñé-Pou, Pilar Pérez-Lozano, Montse Miñarro-Carmona, Encarna García-Montoya, Josep R. Ticó-Grau, Raul Insa Boronat, Josep M. Suñé-Negre   +8 more
doaj   +1 more source

Development of Dihydroquercetin-based Oral tablets and Evalution of the General Toxic Effect

Разработка и регистрация лекарственных средств, 2022
Introduction. Dihydroquercetin is a flavonoid from the group of flavanonols with a wide spectrum of pharmacological activity. Its positive therapeutic profile was established for chronic venous insufficiency, chronic obstructive pulmonary disease and ...
S. A. Abdulrazzak, A. N. Vorobyev, N. I. Sinitsyna, I. V. Sharutin, O. V. Menshova, E. V. Elizarova, Yu. V. Ivanov, A. S. Karamyan, R. A. Abramovich, O. G. Potanina, K. M. Sakanyan   +10 more
doaj   +1 more source

Continuous direct compression as manufacturing platform for sustained release tablets [PDF]

, 2017
This study presents a framework for process and product development on a continuous direct compression manufacturing platform. A challenging sustained release formulation with high content of a poorly flowing low density drug was selected.
Cunningham, C., De Beer, Thomas, Holman, J., Kumar, Ashish, Remon, Jean Paul, Van Snick, Bernd, Vercruysse, Jurgen, Vervaet, Chris   +7 more
core   +1 more source

Effect of Compaction Pressure on the Enzymatic Activity of Pancreatin in Directly Compressible Formulations

Pharmaceutics, 2023
Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated.
Daniel Zakowiecki, Peter Edinger, Tobias Hess, Jadwiga Paszkowska, Marcela Staniszewska, Svitlana Romanova, Grzegorz Garbacz   +6 more
doaj   +1 more source

Chitin and chitosan as direct compression excipients in pharmaceutical applications. [PDF]

Mar Drugs, 2015
Badwan AA, Rashid I, Omari MM, Darras FH.   +3 more
europepmc   +2 more sources