Results 41 to 50 of about 3,524,925 (247)

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Enhancing paracetamol compressibility using the co-drying technique: Impact on tablet release profile from direct compression

German Journal of Pharmaceuticals and Biomaterials
Direct compression is the most acceptable and preferred method for manufacturing tablets. However, the poor flow property and lack of the required compressibility of most active ingredients preclude the direct compression technique.
Shreya Sham Naik, Sandesh Narayan Somnache, Ajeet Madhukar Godbole, Clecy Fernandes   +3 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Dissolution enhancement of glimepiride via refined liquisolid system for bioequivalent tablet [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Glimepiride is a widely used treatment for type II diabetes mellitus and is classified as a Class II drug in the Biopharmaceutical Classification System.
Yulias Ninik Windriyati, M Fatchur Rochman, Ayu Shabrina, Malinda Prihantini, Ridha Hafitriyani, Ambar Sri Wulandari, Putri Rizky Utami   +6 more
doaj   +1 more source

Technology Criteria for the Manufacturing of Rebamipide Film-coated Tablets

Разработка и регистрация лекарственных средств, 2023
Introduction. The current growth of the pharmaceutical market and stiff competition require from drug manufacturers make a more detailed and thorough fine-tuning of existing production lines.
G. V. Trusov, B. V. Brovchenko, Z. M. Kozlova, I. I. Krasnyuk   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

The Role of the Geometric Configuration of Diethylaminoethanol Derivative in the Pharmaceutical Development of a Dosage Form Based on It

Разработка и регистрация лекарственных средств, 2023
Introduction. A comprehensive study of the active pharmaceutical ingredient (API) molecule is one of the defining criteria for pharmaceutical development according to the Quality by Design (QbD) concept and the ICH Q8 framework.
Yu. M. Kotsur, K. M. Tserkovnaya, E. V. Flisyuk, I. A. Titovich, K. O. Sidorov, I. A. Narkevich   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Antimicrobial activity of Ficus exasperata (Vahl) leaf extract in clinical isolates and its development into herbal tablet dosage form

Journal of Medicinal Plants for Economic Development, 2020
Background: Ficus exasperata (Vahl) from the family Moraceae is a herb of ethnobotanical importance with antimicrobial properties. The past studies have been on the phytochemistry and pharmacological activities of the plant, but there is a need to ...
Tolulope O. Ajala, Ayobami J. Olusola, Oluwatoyin A. Odeku   +2 more
doaj   +1 more source

Prediction of the composition of prolonged release tablets based on 4,4'-(propandiamido) sodium dibenzoate using the SeDeM method

Разработка и регистрация лекарственных средств, 2021
Introduction. Direct compression technology is one of the most common tablet technologies. As known, many active pharmaceutical ingredients are not suitable for this technology without the addition of special excipients. A useful tool for determining the
Ju. M. Kotsur, Ju. M. Ladytko, I. A. Narkevich, E. V. Flisyuk   +3 more
doaj   +1 more source