Results 91 to 100 of about 1,137,563 (252)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Factors affecting double-strand break-induced homologous recombination in mammalian cells
BioTechniques, 2005 Double-strand break (DSB)-induced homologous recombination (HR) of direct repeats is a powerful means to achieve gene excision, a critical step in genome engineering.
Christophe Perez +8 more
doaj +1 more source
Penerapan Experiential Marketing Strategy Dan Pengaruhnya Terhadap Kepuasan Dan Loyalitas Studi Pada Pelanggan Bakso Cak Kar Singosari - Malang [PDF]
, 2013 This research aims to: (1) investigate direct influence of experiential marketing on customer satisfaction; (2) investigate direct influence of customer satisfaction on customer loyalty; and (3) investigate direct influence of experiential marketing on ...
Razanah, Z. (Zahrina)
core
SHADE AVOIDANCE 4 is required for proper auxin distribution in the hypocotyl [PDF]
, 2016 The phytohormone auxin is involved in virtually every aspect of plant growth and development. Through polar auxin transport, auxin gradients can be established, which then direct plant differentiation and growth.
Donato, Martin Di +10 more
core +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Bayesian neural network learning for repeat purchase modelling in direct marketing. [PDF]
We focus on purchase incidence modelling for a European direct mail company. Response models based on statistical and neural network techniques are contrasted.
Baesens, Bart +4 more
core
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Effect of Trinucleotide Repeats in the Huntington's Gene on Intelligence
EBioMedicine, 2018 Background: Huntington's Disease (HD) is caused by an abnormality in the HTT gene. This gene includes trinucleotide repeats ranging from 10 to 35, and when expanded beyond 39, causes HD.
Jessica K. Lee +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Non-coding RNA Research, 2018 A hexanucleotide repeat expansion in the first intron/promoter region of C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Andrew G.L. Douglas
doaj +1 more source