Testing public health intervention guidance on increasing the uptake of HIV testing among men who have sex with men. Final fieldwork report [PDF]
This guidance is for NHS and other commissioners, managers and practitioners who have a direct or indirect role in, and responsibility for, increasing the uptake of HIV testing among men who have sex with men.
Dodds, Catherine+2 more
core
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Bayesian neural network learning for repeat purchase modelling in direct marketing. [PDF]
We focus on purchase incidence modelling for a European direct mail company. Response models based on statistical and neural network techniques are contrasted.
Baesens, Bart+4 more
core
Mapping the topography of a protein energy landscape [PDF]
Protein energy landscapes are highly complex, yet the vast majority of states within them tend to be invisible to experimentalists. Here, using site-directed mutagenesis and exploiting the simplicity of tandem-repeat protein structures, we delineate a ...
Bruscolini, P.+7 more
core +3 more sources
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren+16 more
wiley +1 more source
Factors affecting double-strand break-induced homologous recombination in mammalian cells
Double-strand break (DSB)-induced homologous recombination (HR) of direct repeats is a powerful means to achieve gene excision, a critical step in genome engineering.
Christophe Perez+8 more
doaj +1 more source
Stimulation of direct-repeat recombination by RNA polymerase III transcription
Eukaryotic cells have to regulate the progression and integrity of DNA replication forks through concomitantly transcribed genes. A transcription-dependent increase of recombination within protein-coding and ribosomal genes of eukaryotic cells is well documented.
Díaz de la Loza, M. Carmen+2 more
openaire +4 more sources
Air investigation of some alternative methods to agrobacterium and protoplast transformation for introducing exogenous genes into plants, based on the use of pollen as a vector [PDF]
Some of the problems involved in the search for alternative plant transformation vectors have been examined. In particular the use of pregerminated pollen as a direct transformation vector has been investigated.
Morris, S.R.
core
Review of Magnetic Shark Deterrents: Hypothetical Mechanisms and Evidence for Selectivity
Several papers published since 2006 describe effects of magnetic fields on elasmobranchs and assess their utility in reducing negative interactions between sharks and humans, including bycatch reduction.
Courtney, Joshua+2 more
core +1 more source
Extracting Physician Group Intelligence from Electronic Health Records to Support Evidence Based Medicine [PDF]
Evidence-based medicine employs expert opinion and clinical data to inform clinical decision making. The objective of this study is to determine whether it is possible to complement these sources of evidence with information about physician “group ...
Kohane, Isaac S., Weber, Griffin M.
core +2 more sources