Results 101 to 110 of about 1,471,677 (345)

Testing public health intervention guidance on increasing the uptake of HIV testing among men who have sex with men. Final fieldwork report [PDF]

open access: yes, 2011
This guidance is for NHS and other commissioners, managers and practitioners who have a direct or indirect role in, and responsibility for, increasing the uptake of HIV testing among men who have sex with men.
Dodds, Catherine   +2 more
core  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Bayesian neural network learning for repeat purchase modelling in direct marketing. [PDF]

open access: yes
We focus on purchase incidence modelling for a European direct mail company. Response models based on statistical and neural network techniques are contrasted.
Baesens, Bart   +4 more
core  

Mapping the topography of a protein energy landscape [PDF]

open access: yes, 2015
Protein energy landscapes are highly complex, yet the vast majority of states within them tend to be invisible to experimentalists. Here, using site-directed mutagenesis and exploiting the simplicity of tandem-repeat protein structures, we delineate a ...
Bruscolini, P.   +7 more
core   +3 more sources

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Factors affecting double-strand break-induced homologous recombination in mammalian cells

open access: yesBioTechniques, 2005
Double-strand break (DSB)-induced homologous recombination (HR) of direct repeats is a powerful means to achieve gene excision, a critical step in genome engineering.
Christophe Perez   +8 more
doaj   +1 more source

Stimulation of direct-repeat recombination by RNA polymerase III transcription

open access: yesDNA Repair, 2009
Eukaryotic cells have to regulate the progression and integrity of DNA replication forks through concomitantly transcribed genes. A transcription-dependent increase of recombination within protein-coding and ribosomal genes of eukaryotic cells is well documented.
Díaz de la Loza, M. Carmen   +2 more
openaire   +4 more sources

Air investigation of some alternative methods to agrobacterium and protoplast transformation for introducing exogenous genes into plants, based on the use of pollen as a vector [PDF]

open access: yes, 1987
Some of the problems involved in the search for alternative plant transformation vectors have been examined. In particular the use of pregerminated pollen as a direct transformation vector has been investigated.
Morris, S.R.
core  

Review of Magnetic Shark Deterrents: Hypothetical Mechanisms and Evidence for Selectivity

open access: yes, 2014
Several papers published since 2006 describe effects of magnetic fields on elasmobranchs and assess their utility in reducing negative interactions between sharks and humans, including bycatch reduction.
Courtney, Joshua   +2 more
core   +1 more source

Extracting Physician Group Intelligence from Electronic Health Records to Support Evidence Based Medicine [PDF]

open access: yes, 2013
Evidence-based medicine employs expert opinion and clinical data to inform clinical decision making. The objective of this study is to determine whether it is possible to complement these sources of evidence with information about physician “group ...
Kohane, Isaac S., Weber, Griffin M.
core   +2 more sources

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