Results 111 to 120 of about 1,471,677 (345)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Rte-1, a retrotransposon-like element in Caenorhabditis elegans [PDF]

open access: yes, 1996
We have characterized a retrotransposon-like element (Rte-1) in C. elegans. It was identified while we were sequencing the pim related kinase-1 (prk-1) gene. The element is 3,298 bp long and flanked by a 200 bp direct repeat.
Plasterk, Ronald H.A.   +2 more
core   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Sequence diversity and molecular evolution of the merozoite surface antigen 2 of plasmodium falciparum [PDF]

open access: yes, 2018
Eleven new alleles of the Plasmodium falciparum merozoite surface antigen 2 (MSA2) from Papua New Guinea were analyzed by direct sequencing of polymerase chain reaction (PCR) products.
Beck, Hans-Peter   +5 more
core  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Elongated polyproline motifs facilitate enamel evolution through matrix subunit compaction.

open access: yesPLoS Biology, 2009
Vertebrate body designs rely on hydroxyapatite as the principal mineral component of relatively light-weight, articulated endoskeletons and sophisticated tooth-bearing jaws, facilitating rapid movement and efficient predation.
Tianquan Jin   +10 more
doaj   +1 more source

A minimum control ancilla driven quantum computation scheme with repeat-until-success style gate generation

open access: yes, 2014
Some two qubit interactions are singly sufficient for universal quantum computation but not without the use of an ancilla. Recent schemes for universal quantum computation have focused on hybrid physical systems using ancillae.
Halil-Shah, Kerem, Oi, Daniel K. L.
core   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

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