Variable glutamine-rich repeats modulate transcription factor activity [PDF]
, 2015 Excessive expansions of glutamine (Q)-rich repeats in various human proteins are known to result in severe neurodegenerative disorders such as Huntington's disease and several ataxias. However, the physiological role of these repeats and the consequences
Babu, M Madan +11 more
core +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Repeated pattern of $γ$-ray flares in the blazar PKS 1502+106 coincident with the IC190730A neutrino event [PDF]
A&A 694, L10 (2025)It has been demonstrated that at least 10 percent of the brightest blazars in the fourth Fermi-LAT catalog of $\gamma$-ray sources exhibit repeating patterns of $\gamma$-ray flares. These events may be associated with the presence of a non-uniform sheath surrounding a fast jet spine in some blazars.
arxiv +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination. [PDF]
Nucleic Acids Res, 2023 Cerqueira PG +7 more
europepmc +1 more source
Testing public health intervention guidance on increasing the uptake of HIV testing among men who have sex with men. Final fieldwork report [PDF]
, 2011 This guidance is for NHS and other commissioners, managers and practitioners who have a direct or indirect role in, and responsibility for, increasing the uptake of HIV testing among men who have sex with men.
Dodds, Catherine +2 more
core
Stimulation of direct-repeat recombination by RNA polymerase III transcription
DNA Repair, 2009 Eukaryotic cells have to regulate the progression and integrity of DNA replication forks through concomitantly transcribed genes. A transcription-dependent increase of recombination within protein-coding and ribosomal genes of eukaryotic cells is well documented.
Díaz de la Loza, M. Carmen +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Transgenic mice harboring direct repeat substrates reveal key underlying causes of homologous recombination in vivo. [PDF]
DNA Repair (Amst), 2022 Moise AC, Kay JE, Engelward BP.
europepmc +1 more source
, 2014 Some two qubit interactions are singly sufficient for universal quantum computation but not without the use of an ancilla. Recent schemes for universal quantum computation have focused on hybrid physical systems using ancillae.
Halil-Shah, Kerem, Oi, Daniel K. L.
core +1 more source