CrisprVi: a software for visualizing and analyzing CRISPR sequences of prokaryotes
Background Clustered regularly interspaced short palindromic repeats (CRISPR) and their spacers are important components of prokaryotic CRISPR-Cas systems.
Lei Sun+5 more
doaj +1 more source
Optimising repeater schemes for the quantum internet [PDF]
The rate at which quantum communication tasks can be performed using direct transmission is fundamentally hindered by the channel loss. Quantum repeaters allow, in principle, to overcome these limitations, but their introduction necessarily adds an additional layer of complexity to the distribution of entanglement.
arxiv +1 more source
The CAG trinucleotide repeat length in the androgen receptor does not predict the early onset of prostate cancer [PDF]
Objective To relate the repeat length of the androgen-receptor CAG trinucleotide to the age of onset of prostate cancer, stage and grade of disease. Patients and methods After obtaining ethical approval, 265 patients with locally confined or locally ...
Bartlett, J.M.S.+5 more
core +1 more source
Somatic and germinal recombination of a direct repeat in Arabidopsis. [PDF]
Abstract Homologous recombination between a pair of directly repeated transgenes was studied in Arabidopsis. The test construct included two different internal, non-overlapping deletion alleles of npt (neomycin phosphotransferase) flanking an active HPT (hygromycin phosphotransferase) gene.
Ethan R. Signer, Farhah F. Assaad
openaire +3 more sources
Evolution and control of imprinted FWA genes in the genus Arabidopsis. [PDF]
A central question in genomic imprinting is how a specific sequence is recognized as the target for epigenetic marking. In both mammals and plants, imprinted genes are often associated with tandem repeats and transposon-related sequences, but the role of
Ryo Fujimoto+9 more
doaj +1 more source
Background It is hypothesized that the highly conserved inverted repeats (IR) structure of land plant plastid genomes (plastomes) is beneficial for stabilizing plastome organization, whereas the mechanism of the occurrence and stability maintenance of ...
Hong-Rui Zhang+2 more
doaj +1 more source
Targeted Derepression of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat by Pyrrole-Imidazole Polyamides [PDF]
The host factor LSF represses the human immunodeficiency virus type 1 long terminal repeat (LTR) by mediating recruitment of histone deacetylase. We show that pyrrole-imidazole polyamides targeted to the LTR can specifically block LSF binding both in ...
Coull, Jason J.+5 more
core +1 more source
Study the Features of 57 Confirmed CRISPR Loci in 38 Strains of Staphylococcus aureus
Staphylococcus aureus is a foodborne pathogen that causes food contamination and food poisoning, which poses great harm to health, agriculture and other hosts.
Xihong Zhao, Zhixue Yu, Zhenbo Xu
doaj +1 more source
Repetitive DNA profile of the amphibian mitogenome
Background Repetitive DNA elements such as direct and inverted repeat sequences are present in every genome, playing numerous biological roles. In amphibians, the functions and effects of the repeat sequences have not been extensively explored.
Noel Cabañas+5 more
doaj +1 more source
A common trinucleotide repeat expansion within the transcription factor 4 (TCF4, E2-2) gene predicts Fuchs corneal dystrophy. [PDF]
Fuchs endothelial corneal dystrophy (FECD) is a common, familial disease of the corneal endothelium and is the leading indication for corneal transplantation.
Eric D Wieben+6 more
doaj +1 more source