Results 81 to 90 of about 1,471,677 (345)

Periodic Single-Pass Instruction Sequences [PDF]

, 2013
A program is a finite piece of data that produces a (possibly infinite) sequence of primitive instructions. From scratch we develop a linear notation for sequential, imperative programs, using a familiar class of primitive instructions and so-called ...
Bergstra, Jan A., Ponse, Alban
core   +1 more source

Identification of gemin5 as a novel 7-methylguanosine cap-binding protein. [PDF]

PLoS ONE, 2009
A unique attribute of RNA molecules synthesized by RNA polymerase II is the presence of a 7-methylguanosine (m(7)G) cap structure added co-transcriptionally to the 5' end.
Shelton S Bradrick, Matthias Gromeier
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

A spectrum-of-spectrum filtering method to extract direct and multipath arrivals from simulations and measurements

MethodsX, 2023
In measurements and numerical modelling of wave propagation, undesired interference between direct and multipath arrivals can be reduced using Fourier-based signal processing methods.
Eivind Nag Mosland, Per Lunde, Jan Kocbach   +2 more
doaj  

Rapid Molecular Genetic Subtyping of Serotype M1 Group A Streptococcus Strains

Emerging Infectious Diseases, 1999
Serotype M1 group A Streptococcus, the most common cause of invasive disease in many case series, generally have resisted extensive molecular subtyping by standard techniques (e.g., multilocus enzyme electrophoresis, pulsed-field gel electrophoresis). We
Nancy Hoe, Kazumitsu Nakashima, Diana Grigsby, Xi Pan, Shu Jun Dou, Steven Naidich, Marianne Garcia, Emily Kahn, David Bergmire-Sweat, James M. Musser   +9 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

FGF-1 induces expression of LXRα and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes

Journal of Lipid Research, 2009
Fibroblast growth factor 1 (FGF-1) enhances apolipoprotein E (apoE) expression and apoE-HDL biogenesis in autocrine fashion in astrocytes (Ito, J., Y. Nagayasu, R. Lu, A. Kheirollah, M. Hayashi, and S. Yokoyama.
Rui Lu, Jinichi Ito, Noriyuki Iwamoto, Tomoko Nishimaki-Mogami, Shinji Yokoyama   +4 more
doaj  

Leading role of TBP in the Establishment of Complexity in Eukaryotic Transcription Initiation Systems

Cell Reports, 2017
While both archaeal and eukaryotic transcription initiation systems utilize TBP (TATA box-binding protein) and TFIIB (transcription factor IIB), eukaryotic systems include larger numbers of initiation factors.
Eiryo Kawakami, Naruhiko Adachi, Toshiya Senda, Masami Horikoshi   +3 more
doaj   +1 more source

ZNF9 activation of IRES-mediated translation of the human ODC mRNA is decreased in myotonic dystrophy type 2. [PDF]

PLoS ONE, 2010
Myotonic dystrophy types 1 and 2 (DM1 and DM2) are forms of muscular dystrophy that share similar clinical and molecular manifestations, such as myotonia, muscle weakness, cardiac anomalies, cataracts, and the presence of defined RNA-containing foci in ...
Morgan A Sammons, Amanda K Antons, Mourad Bendjennat, Bjarne Udd, Ralf Krahe, Andrew J Link   +5 more
doaj   +1 more source

Programmable Sequence-Specific Transcriptional Regulation of Mammalian Genome Using Designer TAL Effectors [PDF]

, 2010
The ability to direct functional proteins to specific DNA sequences is a long-sought goal in the study and engineering of biological processes. Transcription activator–like effectors (TALEs) from Xanthomonas sp.
AJ Bogdanove, B Gonzalez, C Engler, C Engler, F Zhang, Feng Zhang, GE Meister, George M Church, H Scholze, HJ Lee, J Boch, J Boch, Le Cong, LE Rosen, M Christian, MJ Moscou, ML Maeder, N Xu, P Blancafort, P Romer, P Romer, PA Carr, Paola Arlotta, R Morbitzer, RM Gordley, RR Beerli, S Grizot, S Kay, S Kay, Simona Lodato, Sriram Kosuri, T Li, Z Wei   +32 more
core   +2 more sources