Results 81 to 90 of about 1,137,563 (252)
Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation [PDF]
, 2022 Sebastian Kaluscha +6 more
openalex +1 more source
Corporate Tax Reform and Foreign Direct Investment in Germany – Evidence from Firm-Level Data [PDF]
Does the reduction of the effective tax burden on corporations trigger foreign direct investment? We take the German tax reform of 2000 as a natural experiment in order to isolate the impact of corporate taxation on the investment of foreign-held ...
Clemens Fuest +2 more
core
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Frontiers in Neuroscience, 2019 Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are incurable neurodegenerative conditions. A non-coding hexanucleotide (GGGGCC) repeat expansion in the c9orf72 gene is the most common genetic cause of ALS/FTD. We present a cellular
Peter O. Bauer +5 more
doaj +1 more source
Periodic Single-Pass Instruction Sequences [PDF]
, 2013 A program is a finite piece of data that produces a (possibly infinite) sequence of primitive instructions. From scratch we develop a linear notation for sequential, imperative programs, using a familiar class of primitive instructions and so-called ...
Bergstra, Jan A., Ponse, Alban
core +1 more source
Transcription as a Threat to Genome Integrity [PDF]
, 2016 Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés +1 more
core +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Journal of Lipid Research, 2002 Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PL222222222216) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) and ...
Puiying A. Mak +3 more
doaj +1 more source
Influencing recidivist drink drivers' entrenched behaviours : the self-reported outcomes of three countermeasures [PDF]
, 2004 Concern remains regarding the efficacy of drink driving countermeasures to produce lasting change for repeat offenders, as a wide array of countermeasures have been developed that demonstrate varying levels of success in reducing re-offence rates.
Freeman, James Edwin
core +1 more source
Hysterectomy, endometrial ablation, and levonorgestrel releasing intrauterine system (Mirena) for treatment of heavy menstrual bleeding : cost effectiveness analysis [PDF]
, 2011 Peer reviewedPublisher ...
Barton, P M +7 more
core +2 more sources