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Directed Evolution of an RNA Enzyme

Science, 1992
An in vitro evolution procedure was used to obtain RNA enzymes with a particular catalytic function. A population of 10 13 variants of the Tetrahymena ribozyme, a group I ribozyme that catalyzes sequence-specific cleavage of RNA via a phosphoester transfer mechanism, was generated.
A A, Beaudry, G F, Joyce
openaire   +2 more sources

Directed Evolution

Journal of Applied Philosophy, 1996
Though we humans are immensely more gifted than other animals, yet we are not the outcome of an inevitable selection of the ‘fittest’. Nor on the other hand is our importance diminished by our evolutionary inheritance. Besides, we are already here! Faith in inevitable progress is a ‘scientific’, not a Christian, delusion.
openaire   +1 more source

Directed evolution

Nature Biotechnology
Aaron M. Leconte, Clair M. Colee
  +5 more sources

Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species

Cell, 2021
Mohammadsharif Tabebordbar   +2 more
exaly  

Droplet Microfluidics and Directed Evolution of Enzymes: An Intertwined Journey

Angewandte Chemie - International Edition, 2021
Ariane Stucki   +2 more
exaly  

Directed Evolution

2013
L. Gold, J. Walker
openaire   +1 more source

Directed Evolution of Microbial Communities

Annual Review of Biophysics, 2021
Alvaro Sanchez   +2 more
exaly  

Directed evolution

2022
Andrea Baier, Ryszard Szyszka
openaire   +2 more sources

Directed Evolution: Methodologies and Applications

Chemical Reviews, 2021
Yajie Wang, Pu Xue, Mingfeng Cao
exaly  

The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes

Angewandte Chemie - International Edition, 2020
Ge Qu   +2 more
exaly  

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