Results 61 to 70 of about 608,783 (278)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Understanding normal and restricted normal products in soft directed graphs
Journal of Nigerian Society of Physical SciencesThis paper extends the framework of soft set theory to directed graphs by introducing and analyzing the concepts of the normal product and restricted normal product of soft directed graphs.
Jinta Jose +3 more
doaj +1 more source
On incidence algebras and directed graphs
International Journal of Mathematics and Mathematical Sciences, 2002 The incidence algebra I(X,ℝ) of a locally finite poset (X,≤) has been defined and studied by Spiegel and O'Donnell (1997). A poset (V,≤) has a directed graph (Gv,≤) representing it.
Ancykutty Joseph
doaj +1 more source
Decremental Single-Source Reachability in Planar Digraphs
, 2017 In this paper we show a new algorithm for the decremental single-source reachability problem in directed planar graphs. It processes any sequence of edge deletions in $O(n\log^2{n}\log\log{n})$ total time and explicitly maintains the set of vertices ...
Italiano, Giuseppe F. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Extrema property of the k-ranking of directed paths and cycles
AKCE International Journal of Graphs and Combinatorics, 2016 A k-ranking of a directed graph G is a labeling of the vertex set of G with k positive integers such that every directed path connecting two vertices with the same label includes a vertex with a larger label in between.
Breeanne Baker Swart +3 more
doaj +1 more source
Scalable Graph Convolutional Networks With Fast Localized Spectral Filter for Directed Graphs
IEEE Access, 2020 Graph convolutional neural netwoks (GCNNs) have been emerged to handle graph-structured data in recent years. Most existing GCNNs are either spatial approaches working on neighborhood of each node, or spectral approaches based on graph Laplacian ...
Chensheng Li +4 more
doaj +1 more source
Directed Graph Exploration [PDF]
, 2012 We study the problem of exploring all nodes of an unknown directed graph. A searcher has to construct a tour that visits all nodes, but only has information about the parts of the graph it already visited. The goal is to minimize the cost of such a tour.
Klaus-Tycho Förster, Roger Wattenhofer
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source