Results 71 to 80 of about 1,263,669 (205)
Modeling U.S. Soy-Based Markets with Directed Acyclic Graphs and Bernanke Structural VAR Methods: The Impacts of High Soy Meal and Soybean Prices [PDF]
Advanced methods that combine directed acyclic graphs with Bernanke structural vector autoregression models are applied to a monthly system of three U.S.
Reeder, John +3 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Pebbling on Directed Graphs [PDF]
, 2023 Consider a finite connected graph G whose vertices are labeled with non-negative integers representing the number of pebbles on each vertex. A pebbling move on a graph G is defined as the removal of two pebbles from one vertex and the addition of one ...
Higgins, Aparna, Gunda, Gayatri
core +1 more source
BMC Bioinformatics, 2019 Background Detection of central nodes in asymmetrically directed biological networks depends on centrality metrics quantifying individual nodes’ importance in a network.
Eun-Youn Kim +2 more
doaj +1 more source
Dynamic Relationships Among Selected U.S. Commodity-Based, Value Added Markets: Applying Directed Acyclic Graphs to a Time Series Model [PDF]
This paper demonstrates the application of a recently developed methodology, the combination of directed acyclic graphs (DAGs) with Bernanke structural vector autoregression (VAR) models, to model a system of U.S.
Payne, Warren S. +2 more
core
Counting Dominating Sets in Directed Path Graphs [PDF]
, 2022 A dominating set of a graph is a set of vertices such that every vertex not in the set has at least one neighbor in the set. The problem of counting dominating sets is #P-complete for chordal graphs but solvable in polynomial time for its subclass of ...
Lin, Min-Sheng
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Covering partially directed graphs with directed paths
, 2006 We consider graphs which contain both directed and undirected edges (partially directed graphs). We show that the problem of covering the edges of such graphs with a minimum number of edge-disjoint directed paths respecting the orientations of the ...
Romeo Rizzi +2 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source