Results 71 to 80 of about 608,783 (278)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
BMC Bioinformatics, 2019 Background Detection of central nodes in asymmetrically directed biological networks depends on centrality metrics quantifying individual nodes’ importance in a network.
Eun-Youn Kim +2 more
doaj +1 more source
Algorithms, 2020 In a previous paper we defined the black and white SAT problem which has exactly two solutions, where each variable is either true or false. We showed that black and white 2-SAT problems represent strongly connected directed graphs. We presented also the
Gábor Kusper, Csaba Biró
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Cut-Matching Games on Directed Graphs [PDF]
, 2010 We give O(log^2 n)-approximation algorithm based on the cut-matching framework of [10, 13, 14] for computing the sparsest cut on directed graphs. Our algorithm uses only O(log^2 n) single commodity max-flow computations and thus breaks the multicommodity-
Louis, Anand
core
Packing and Covering a Given Directed Graph in a Directed Graph
SIAM Journal on Discrete MathematicsFor every fixed $k \ge 4$, it is proved that if an $n$-vertex directed graph has at most $t$ pairwise arc-disjoint directed $k$-cycles, then there exists a set of at most $\frac{2}{3}kt+ o(n^2)$ arcs that meets all directed $k$-cycles and that the set of $k$-cycles admits a fractional cover of value at most $\frac{2}{3}kt$.
openaire +3 more sources
On bisections of directed graphs
European Journal of Combinatorics, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jianfeng Hou, Shufei Wu, Guiying Yan
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Directed Acyclic Outerplanar Graphs Have Constant Stack Number [PDF]
TheoretiCSThe stack number of a directed acyclic graph $G$ is the minimum $k$ for which there is a topological ordering of $G$ and a $k$-coloring of the edges such that no two edges of the same color cross, i.e., have alternating endpoints along the topological ...
Paul Jungeblut +2 more
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The direct expansion of graphs
Discrete Mathematics, 2002 Expansion procedures introduced by \textit{H. M. Mulder} [The expansion procedure for graphs, in: Contemporary methods in graph theory. In honour of Prof. Dr. K. Wagner, 459-477 (1990; Zbl 0744.05064)] proved to be useful in recognition of median, quasi-median and partial Hamming graphs.
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source