Results 101 to 110 of about 495,896 (276)

Collective flow in heavy ion reactions and the properties of excited nuclear matter [PDF]

, 1996
Quantum Molecular Dynamics (QMD) calculations of central collisions between heavy nuclei are used to study fragment production and the creation of collective flow.
Bass, Steffen A., Bleicher, Marcus, Brandstetter, Mathias, Ernst, Christoph, Gerland, Lars, Greiner, Walter, Konopka, Jens, Soff, Sven, Spieles, Christian, Stöcker, Horst, Weber, Henning, Winckelmann, Luke Andreas   +11 more
core   +1 more source

Directed transport as a mechanism for protein folding in vivo

, 2009
We propose a model for protein folding in vivo based on a Brownian-ratchet mechanism in the multidimensional energy landscape space. The device is able to produce directed transport taking advantage of the assumed intrinsic asymmetric properties of the ...
Alberts B., Bhutani N., Ellis R. J., Ernesto González-Candela, Kramer G., Lapanje S., Levinthal C., van Kampen N. G., Visscher K., Víctor Romero-Rochín   +9 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Improving Hydrolytic Activity and Enantioselectivity of Epoxide Hydrolase from Phanerochaete chrysosporium by Directed Evolution

Molecules
Epoxide hydrolases (EHs) catalyze the conversion of epoxides into vicinal diols. The epoxide hydrolase gene from P. chrysosporium was previously cloned and subjected to site-directed mutation to study its enzyme activity, but the results were ...
Huanhuan Shao, Pan Xu, Xiang Tao, Xinyi He, Chunyan Pu, Shaorong Liang, Yingxin Shi, Xiaoyan Wang, Hong Feng, Bin Yong   +9 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Remarks on the non-equilibrium effects and collision dynamics in heavy-ion collisions

, 2010
We study the beam energy dependence of equilibration process and space-time characteristics of participant and spectator matter. For this, we simulated the semi-central collisions of $^{40}Ca+ ^{40}Ca$ at incident energies of 400, 600 and 1000 AMeV ...
Kaur, Mandeep, Vermani, Yogesh K.
core   +1 more source

Analytical study of the effect of recombination on evolution via DNA shuffling

, 2003
We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selection, recombination and point mutations.
A. S. Kondrashov, D. A. Kessler, D. S. Falconer, E. E. Shnol, F. Sun, H. Lodish, H. Mühlenbein, H.-G. Beyer, J. F. Crow, L. Chao, M. Barlow, M. Kimura, N. H. Barton, P. H. Von Hippel, R. Büger, R. J. Redfield, S. P. Otto, S. P. Otto, W. P. C. Stemmer   +18 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

{Co4O4} Cubanes in a conducting polymer matrix as bio-inspired molecular oxygen evolution catalysts

Nature Communications
Exploration of efficient molecular water oxidation catalysts for long-term application remains a key challenge for the conversion of renewable energy sources into fuels.
Shangkun Li, Zeyi Zhang, Walker R. Marks, Xinan Huang, Hang Chen, Dragos C. Stoian, Rolf Erni, Carlos A. Triana, Greta R. Patzke   +8 more
doaj   +1 more source

The asexual genome of Drosophila

, 2017
The rate of recombination affects the mode of molecular evolution. In high-recombining sequence, the targets of selection are individual genetic loci; under low recombination, selection collectively acts on large, genetically linked genomic segments ...
Lässig, Michael, Mustonen, Ville, Schiffels, Stephan   +2 more
core   +1 more source