Results 71 to 80 of about 26,182 (278)
Indium-mediated C-allylation of melibiose
Beilstein Journal of Organic Chemistry, 2019 The indium-mediated allylation reaction has been applied to melibiose, a disaccharidic substrate. This elongation methodology allows for a short, efficient and diastereoselective approach towards complex glycosylated carbohydrate structures.
Christian Denner +3 more
doaj +1 more source
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
Chemistry &Biodiversity, EarlyView.ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos +8 more
wiley +1 more source
IDENTIFICATION AND DIFFERENTIATION OF UNDERIVATIZED DIASTEROMERIC
Vitae, 2010 Sugars are important molecules with remarkable cell signals pathway functions in higher organisms. The structural complexity of sugar represented by its isomeric, anomeric and diasteromeric configurations deserve the implementation of modern, rapid and ...
Guillermo L. MONTOYA P. +2 more
doaj
Reviewing Glycosyl‐Inositols: Natural Occurrence, Biological Roles, and Synthetic Techniques
ChemBioChem, Volume 26, Issue 6, March 15, 2025.Overall, this comprehensive review underscores the significance of glycosyl inositols as versatile molecules with diverse biological functions and promising applications in scientific research and industry. Methods for their chemical and enzymatic synthesis are also reviewed, highlighting recent advances and challenges in the field.
Alfonso Miranda‐Molina +3 more
wiley +1 more source
Deciphering the Interplay Between G‐Quadruplexes and Natural/Synthetic Polyamines
ChemBioChem, Volume 26, Issue 7, April 1, 2025.The interplay between polyamines and G‐quadruplexes has been largely overlooked in the literature, even though PAs are ubiquitous metabolites in living cells and G4s are transient regulatory elements. Herein, we compile the investigations connecting G4s and biogenic polyamines or synthetic G4 ligands containing polyamines.
Ariadna Gil‐Martínez +4 more
wiley +1 more source
ChemBioChem, EarlyView.The tetrasaccharide linkage region of proteoglycans is synthesized through a series of well‐controlled enzymatic reactions in nature. The expression, activity, and substrate profile of these biosynthetic enzymes and the latest development of chemoenzymatic synthesis of linkage region‐bearing glycopeptides are summarized in this review.
Po‐han Lin, Xuefei Huang
wiley +1 more source
Instant determination of the potential biomarker heparan sulfate in human plasma by a mix-and-read fluorescence assay [PDF]
arXiv, 2017 Heparan sulfate (HS) is a linear, polydisperse sulfated polysaccharide belonging to the glycosaminoglycan family. HS proteoglycans are ubiquitously found at the cell surface and extracellular matrix in animal species. HS is involved in the interaction with a wide variety of proteins and the regulation of many biological activities.
arxiv
ChemBioChem, EarlyView.This analysis reveals structural heterogeneity in the lipopolysaccharide lipid A from the cold‐adapted Gram‐negative bacterium Polaribacter sp. SM1127, with variations in fatty acid chain number, length, branching, saturation, and hydroxylation degree, likely aiding bacterial adaptation to cold environmental stressors. Lipopolysaccharide is shown to be
Roberta Cirella +9 more
wiley +1 more source
A bacterial ABC transporter enables import of mammalian host glycosaminoglycans
Scientific Reports, 2017 Glycosaminoglycans (GAGs), such as hyaluronan, chondroitin sulfate, and heparin, constitute mammalian extracellular matrices. The uronate and amino sugar residues in hyaluronan and chondroitin sulfate are linked by 1,3-glycoside bond, while heparin ...
Sayoko Oiki +4 more
doaj +1 more source
Influence of sugars on the reddening of triturated florets of dyer's saffron flowers
Acta Societatis Botanicorum Poloniae, 2014 Pentoses, hexoses and disaccharides were administered to the triturated florets of dyer's saffon (Carthamus tinctorius) and their effects on enzyme-catalyzed floret reddening examined spectrophotometically.
Koshi Saito
doaj +1 more source