Results 71 to 80 of about 45,126 (263)

Seventy Years of Passing on the Torch， Striving Forward in the New Era — Thoughts on the Construction of Forensic Medicine at Sun Yat-sen University

Fayixue Zazhi
The forensic medicine discipline of Sun Yat-sen University is one of the important origins of modern and contemporary forensic medicine education in China, and it is a microcosm of the development of forensic medicine education, research and ...
SUN Hong-yu, ZHAO Hu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Rural Constructions in the Professional Training of Students from a Principal Integrating Discipline Perspective.

Agrisost, 2021
Context: The job insertion of students in the Degree of Education Construction in rural constructions, from the perspective of the professional teaching-learning process of the principal integrating discipline, favors their professional training.
Nurbia Ivia Zaragoza Morales, Miguel Alejandro Cruz Cabezas, Orlando Martínez Cuba   +2 more
doaj  

What is to be Done? : Climate Change for Beginners

Construction Economics and Building, 2015
Bon, Ranko (2014). What is to be done? : Climate Change for Beginners. Hesperiaedu, Belgrade. 150 pages.
Abbas Elmualim
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Construction History in Spain

, 2015
En Espagne, l’histoire de la construction constitue une discipline à part entière, consolidée durant ces vingt dernières années en raison des nombreuses manifestations dédiées. Mais des obstacles pourraient la menacer : l’absence d’enseignement, l’amateurisme et la fragmentation. L’enseignement est envisagé dès la formation initiale.
Huerta Fernández, Santiago, Gil Crespo, Ignacio Javier   +1 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Domestic and International Experience and Inspiration on the Innovation Training in Medical-Engineering Talents

Yixue yu zhexue
Medical physics is fundamental for modern clinical services and technological progress in diagnostic and therapeutic radiology, such as radiotherapy, nuclear medicine, and medical imaging.
Sheng HUANG, Tian LI, Zhenyu YANG, Pengbo HE, Yanglin CHEN, Yibao ZHANG   +5 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source