Results 131 to 140 of about 92,114,249 (286)
Brain Research BulletinResearch over the past few decades has focused on elucidating the role of the blood-brain barrier (BBB) in neuroprotection, regulation of the brain microenvironment, and mediation of the selective permeability of substances, including drug molecules ...
Kiran Marathe +3 more
doaj +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Organ-on-a-Chip Applications in Microfluidic Platforms
MicromachinesMicrofluidic technology plays a crucial role in organ-on-a-chip (OoC) systems by replicating human physiological processes and disease states, significantly advancing biomedical research and drug discovery. This article reviews the design and fabrication
Ling An, Yi Liu, Yaling Liu
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A portable respiratory monitoring device based on a flexible PZT sensor captures pressure‐ and temperature‐related airflow responses in a single waveform. Polarity‐opposed piezoelectric and pyroelectric components generate a narrow transient spike and a broad quasi‐steady peak during both inhalation and exhalation. This dual‐component structure enables
Minyu Li +7 more
wiley +1 more source
CRISPR in 3D: Innovations in Disease Modelling and Personalized Medicine
BioTechniquesThe CRISPR-Cas system of genetic engineering has had a significant impact on science and society since its advent in 2013. CRISPR integration with 3D culture systems such as organ-on-a-chips, as well as fast emerging commercial technologies, has ...
Louis J Gautier
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova +4 more
wiley +1 more source
Adaptable Switch boxes as on-chip routing nodes for networks-on-chip
, 2005 Eickhoff R, Niemann J-C, Porrmann M, Rückert U. Adaptable Switch boxes as on-chip routing nodes for networks-on-chip. In: Rettberg A, Zanella MC, Rammig FJ, eds. From Specification to Embedded Systems Application .
Eickhoff, Ralf +6 more
core +1 more source
Exploring microorganism–host interactions: Emerging organoid models and analytical approaches
mLifeMicroorganisms play a vital role in human health through their interactions with the body. Studies of host–microbe mechanisms and interactions are crucial for advancing health management. Recently, the organoid‐based models have provided new platforms in
Yue Shi +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină +2 more
wiley +1 more source