Results 111 to 120 of about 195,333 (281)

Bone-on-a-Chip Systems for Hematological Cancers

Biosensors
Hematological malignancies originating from blood, bone marrow, and lymph nodes include leukemia, lymphoma, and myeloma, which necessitate the use of a distinct chemotherapeutic approach.
Gül Kozalak, Ali Koşar
doaj   +1 more source

2019 Proceedings of the 26th Annual Summer Research Symposium [PDF]

, 2019
The 2019 Dr. Charles S. Weiss Summer Research Symposium, now in its 26th year, the symposium is a college-wide event that brings together faculty and students from all disciplines at Holy Cross and provides an opportunity to celebrate their ...
College of the Holy Cross
core   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight   +29 more
wiley   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

Artificial Intelligence‐based Online Symptom Assessment Tools for Systemic Lupus Erythematosus (SLE) diagnosis: Patient Perspectives

Arthritis Care &Research, Accepted Article.
Objective The objective of this article is to identify perceptions of SLE patients regarding artificial intelligence (AI)‐based online symptom assessment tools, and the potential of these tools to address diagnostic barriers. Methods Adults from our SLE research cohort were invited to participate in 60‐90 minute virtual focus groups concerning their ...
Olivia A. Stein, Jennifer LF. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Nat Rev Drug Discov [PDF]

Improving the effectiveness of preclinical predictions of human drug responses is critical to reducing costly failures in clinical trials. Recent advances in cell biology, microfabrication and microfluidics have enabled the development of microengineered

core  

The effect of Dinaciclib and Palbociclib on normal and breast cancer cells in 2D and 3D culture. [PDF]

, 2018
Thesis. M.S. American University of Beirut. Department of Biology, 2018. T:6875Advisor : Dr. Rabih Talhouk, Professor, Biology ; Co-Advisor : Dr. Raya Saab, Associate Professor, Anatomy, Cell Biology and Physiological Science ; Members of Committee : Dr.
Fatfat, Zaynab Abd El Rahman
core  

A return to normality: A descriptive qualitative interview study exploring the patient experience of gout flare resolution

Arthritis Care &Research, Accepted Article.
Objectives While the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semi‐structured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K Stamp, N Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

Advanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source