Results 121 to 130 of about 195,333 (281)

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

Translational Pharmacology [PDF]

, 2017
Alastair G. Stewart
core   +2 more sources

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Organ-on-Chip Technology for Aerobic Intestinal Host - Anaerobic Microbiota Research [PDF]

, 2021
Bossink, Elsbeth G.B.M., Odijk, Mathieu, Segerink, Loes   +2 more
core   +2 more sources

Animal Experimentation: Working Towards a Paradigm Change [PDF]

, 2019
Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans.
Herrmann, Kathrin, (ed.), Jayne, Kimberley, (ed.)   +1 more
core   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Organ‐on‐a‐Chip Technology and Global Multi‐Omics: Current Applications and Future Directions

MedComm
Biomedical research models are undergoing continuous evolution, while conventional models (two‐dimensional/ three‐dimensional cultures and animal studies) face limitations in physiological relevance and ethical constraints.
Xuxia Cao, Congmin Xia, Caifeng Li, Shiwen Deng, Junxian Cao, Hongjun Yang, Shaoping Wang, Peng Chen   +7 more
doaj   +1 more source

Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction [PDF]

BackgroundThe placental barrier is a critical interface that regulates drug transport between maternal and fetal circulation and is an important component in assessing fetal drug-exposure risk. Since pregnant women are often excluded from clinical trials,
Fei Wang, Jiao Zhang, Shiran Li, Siyu Zeng, Yong Yang, Yue Wu, Yujie Yang, Zhimin Li   +7 more
core   +1 more source

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

Advanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

Organ-on-a-Chip Applications in Microfluidic Platforms

Micromachines
Microfluidic technology plays a crucial role in organ-on-a-chip (OoC) systems by replicating human physiological processes and disease states, significantly advancing biomedical research and drug discovery. This article reviews the design and fabrication
Ling An, Yi Liu, Yaling Liu
doaj   +1 more source