Results 201 to 210 of about 207,508 (246)

Rethinking non-human primate models for emerging viral infections after COVID-19. [PDF]

Lab Anim Res
Kim DY, Hong JJ.
europepmc   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

Advanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun, Hengjie Xu, Sheng Yang, Jiahui Zhou, Chuanxin Tian, Hongxu Nie, Chi Jin, Tuo Wang, Zhihao Chen, Junwei Tang, Yifei Feng, Xiaowei Wang, Yueming Sun   +12 more
wiley   +1 more source

Longitudinal Assessment of EGFR and MET Transcriptional Activity Using Cell-Free Chromatin Immunoprecipitation in Two Patients with EGFR-Mutated Non-Small Cell Lung Cancer. [PDF]

Cancers (Basel)
Pedersen E, Maansson CT, Meldgaard P, Sorensen BS.   +3 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Blood and Urine Transcriptomes Reveal Complementary Host Responses and a Creatinine-Associated Urinary Transcriptional Axis in Sepsis. [PDF]

Diagnostics (Basel)
Beloussov V, Strochkov V, Sandybayev N, Lavrinenko A, Aitpenov T, Solomadin M.   +5 more
europepmc   +1 more source

Germline and somatic variants in DNMT3A and other clonal haematopoiesis of indeterminate potential genes contribute to pulmonary arterial hypertension. [PDF]

Eur Heart J
Al-Qazazi R, Emon IM, Potus F, Martin AY, Lima PDA, Vlasschaert C, Ott BP, Chen KH, Wu D, Dasgupta A, Noordhof C, Jefferson L, Buttigieg MM, McNaughton AJM, Hindmarch CCT, Bick AG, Nichols WC, Chung WK, Hassoun PM, Damico RL, Zhu N, Shen Y, Rauh MJ, Archer SL.   +23 more
europepmc   +1 more source

Microfluidic intestinal-chips as next-generation modeling strategies: Multifaceted emerging applications in food research, functional foods and personalized nutrition. [PDF]

Curr Res Food Sci
Feng J, Zhu H, Peng Y, Lin L, Yao J, Fan X, Shen J, Xue J, Wang Z, Shen G, Shen Q.   +10 more
europepmc   +1 more source

The proteomic architecture of clonal hematopoiesis: a systematic review of niche remodeling and multi-compartment predictors of malignant transformation. [PDF]

Front Med (Lausanne)
Husein JH, Khayata RM, Jahangir A, Mansour GK, Hajjar AW, Sajid MR.   +5 more
europepmc   +1 more source

Molecular basis of coronary artery disease-malignancy comorbidity: inflammation, immunometabolism, thrombosis, and cardio-oncology translation. [PDF]

Front Immunol
Li J, Zhao Y, Bai M.
europepmc   +1 more source