Results 221 to 230 of about 204,111 (283)

Microfluidics for Blood Disorders and Hematological Disease Monitoring and Modeling. [PDF]

Int J Mol Sci
Hu M, Henderson N, Soper SA, Witek MA.
europepmc   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Clonal Hematopoiesis (CHIP) in Pulmonary Embolism and CTEPH: Evidence, Mechanisms, and Risk Stratification. [PDF]

Int J Mol Sci
Szarpak L, Jach ME, Skoczylas M, Radej S, Pruc M.   +4 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model. [PDF]

Proc Natl Acad Sci U S A
Zlotnick HM, Goddard DN, Calo CJ, Dhand AP, Davidson MD, Solsona-Pujol A, Makhoul JT, Weppner HK, Wong M, Scanzello CR, Hind LE, Burdick JA.   +11 more
europepmc   +1 more source

Clonal Hematopoiesis and Risk of Incident Pericarditis and Myocarditis in 2 US Biobank Cohorts.

JAMA Cardiol
Pershad Y, Zhao K, Heimlich JB, Bick AG.
europepmc   +1 more source

Prime time for the use of statins in MPNs: from comorbidity drugs to disease-modifying partners. [PDF]

Blood Adv
Hasselbalch HC.
europepmc   +1 more source

Ageing Through the Looking-Glass: The Different Flavours of Clonal Haematopoiesis. [PDF]

Aging Cell
Singh J, Curtis DJ, Thao LTP, Wood EM, McQuilten ZK.   +4 more
europepmc   +1 more source

Diagnostic accuracy of chip hybridization from formalin-fixed paraffin embedded bioptic specimens in a cohort with predominantly extrapulmonary mycobacterial disease. [PDF]

BMC Microbiol
Winkelmann R, Blasczok B, Winter M, Wild P, Vehreschild MJGT, Kempf VAJ, Wichelhaus TA, Idris R, Wetzstein N.   +8 more
europepmc   +1 more source