Results 221 to 230 of about 92,114,249 (286)

Chip Edisi Januari s.d. Juni 2009

, 2011
CHIP
core  

Clonal Hematopoiesis in Cardiovascular Risk: Focus on Inflammatory Mechanisms. [PDF]

J Clin Med
Sinnadurai S, Honigberg MC, Meijers WC, Merkus D, Niroula A, Sharma HS, Jankowski P, Van Der Spek PJ, de Boer RA, Manintveld OC, Kaminski KA.   +10 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Biomimetic flowing vessel-on-a-chip recruiting glycocalyx features for investigating dexmedetomidine function. [PDF]

Mater Today Bio
Zhang Y, Lin L, Gan J, Ding X, Wang W.
europepmc   +1 more source

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

Advanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang, Yuxiang Ren, Shofarul Wustoni, Atheer Alqatari, Adel Hama, Yazhou Wang, Long Chen, Jessica Parrado Agudelo, Luca Salvigni, Keying Guo, Ashraf Dada, Stefan T. Arold, Raik Grünberg, Sahika Inal   +13 more
wiley   +1 more source

Lung-On-A-Chip Technologies for Disease Modeling and Drug Development

Biomedical Engineering and Computational Biology, 2016
Dipasri Konar, Mahesh Devarasetty, Didem V. Yildiz, Anthony Atala, Sean V. Murphy   +4 more
doaj  

Human Multi-Organ-on-a-Chip Platforms for Next-Generation Drug Delivery Strategies. [PDF]

Theranostics
Mitchell CS, Yoo HI, Gracia Diaz C, Green JJ, Kim DH.   +4 more
europepmc   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Association of infection frequency and incident clonal hematopoiesis of indeterminant potential. [PDF]

Exp Hematol
Lapite A, Burk VA, DeCuir J, Ishigami J, Saadatagah S, Natarajan P, Ballantyne CM, Platz EA, King KY.   +8 more
europepmc   +1 more source