Results 31 to 40 of about 1,245,538 (288)
Modeling infectious disease dynamics [PDF]
Science, 2020 The spread of the coronavirus SARS-CoV-2 has predictable ...
openaire +2 more sources
Applications of miRNAs in cardiac development, disease progression and regeneration
Stem Cell Research & Therapy, 2019 Development of the complex human heart is tightly regulated at multiple levels, maintaining multipotency and proliferative state in the embryonic cardiovascular progenitors and thereafter suppressing progenitor characteristics to allow for terminal ...
Jeremy Kah Sheng Pang +2 more
doaj +1 more source
Enhanced vaccine control of epidemics in adaptive networks [PDF]
, 2009 We study vaccine control for disease spread on an adaptive network modeling disease avoidance behavior. Control is implemented by adding Poisson distributed vaccination of susceptibles.
Ira B. Schwartz +4 more
core +3 more sources
Statistical Disease Progression Modeling in Alzheimer Disease [PDF]
Frontiers in Big Data, 2020 Background: The characterizing symptom of Alzheimer disease (AD) is cognitive deterioration. While much recent work has focused on defining AD as a biological construct, most patients are still diagnosed, staged, and treated based on their cognitive symptoms.
Lars Lau Raket, Lars Lau Raket
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
Looking Back: Disease Modeling [PDF]
Cell Stem Cell, 2017 Over the past decade, the growth of stem cell-based models of human disorders has contributed to novel drug discovery and precision medicine possibilities. For our tenth anniversary, we asked authors who cited a selection of our most popular papers in this area about how these studies influenced them.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
BMC Infectious Diseases, 2017 Background Individual-based models (IBMs) are useful to simulate events subject to stochasticity and/or heterogeneity, and have become well established to model the potential (re)emergence of pathogens (e.g., pandemic influenza, bioterrorism). Individual
Lander Willem +4 more
doaj +1 more source
A pair formation model with recovery: Application to mpox
Epidemics, 2023 The current global outbreaks of mpox is a unique infectious disease in the way it seems to be transmitting: it has been observed to be highly concentrated in communities of men who have sex with men (MSM) through pair formation, and also provides long ...
Matthew I. Betti +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source