Results 31 to 40 of about 567,069 (269)
Fitting homocysteine to disease models, as well as adjusting the models to the disease [PDF]
Journal of Molecular Medicine, 2015 Homocysteine is a nonprotein α-amino acid and differs from cysteine by having an additional methylene bridge. Homocysteine is not present in the diet, and all homocysteine in the body is biosynthesized from the essential amino acid methionine. Homocysteine is a product of methionine demethylation and is recycled into methionine or alternatively ...
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Evaluation of Models of Parkinson's Disease [PDF]
Frontiers in Neuroscience, 2016 Parkinson's disease is one of the most common neurodegenerative diseases. Animal models have contributed a large part to our understanding and therapeutics developed for treatment of PD. There are several more exhaustive reviews of literature that provide the initiated insights into the specific models; however a novel synthesis of the basic advantages
Jagmag, Shail A. +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley +1 more source
A pair formation model with recovery: Application to mpox
Epidemics, 2023 The current global outbreaks of mpox is a unique infectious disease in the way it seems to be transmitting: it has been observed to be highly concentrated in communities of men who have sex with men (MSM) through pair formation, and also provides long ...
Matthew I. Betti +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
BMC Infectious Diseases, 2017 Background Individual-based models (IBMs) are useful to simulate events subject to stochasticity and/or heterogeneity, and have become well established to model the potential (re)emergence of pathogens (e.g., pandemic influenza, bioterrorism). Individual
Lander Willem +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark +9 more
wiley +1 more source
Cell & Bioscience, 2021 The COVID-19 pandemic is having a tremendous impact on humanity. Although COVID-19 vaccines are showing promising results, they are not 100% effective and resistant mutant SARS-CoV-2 strains are on the rise.
Joyce van de Leemput, Zhe Han
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The Roles of Histone Lysine Methyltransferases in Heart Development and Disease
Journal of Cardiovascular Development and Disease, 2023 Epigenetic marks regulate the transcriptomic landscape by facilitating the structural packing and unwinding of the genome, which is tightly folded inside the nucleus. Lysine-specific histone methylation is one such mark.
Jun-yi Zhu +2 more
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Mathematical Modeling of Autoimmune Diseases [PDF]
Symmetry, 2020 The human organism is a very complex system. To be in good health, its components must function properly. One of the most important systems of an organism is the immune system. It protects the body from the harmful effects of various external and internal agents.
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