Results 21 to 30 of about 659,696 (286)
Bayesian Modelling of Inseparable Space-Time Variation in Disease Risk [PDF]
, 1998 This paper proposes a unified framework for a Bayesian analysis of incidence or mortality data in space and time. We introduce four different types of prior distributions for space $\times$ time interaction in extension of a model with only main effects.
Knorr-Held, Leonhard
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Quantifying the impact of physical distance measures on the transmission of COVID-19 in the UK
BMC Medicine, 2020 Background To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether these measures might be sufficient to control the epidemic by estimating their impact on
Christopher I. Jarvis +7 more
doaj +1 more source
Advocating the need of a systems biology approach for personalised prognosis and treatment of B-CLL patients [PDF]
, 2012 The clinical course of B-CLL is heterogeneous. This heterogeneity leads to a clinical dilemma: can we identify those patients who will benefit from early treatment and predict the survival?
Goltsov, Alexey +6 more
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Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease [PDF]
, 2014 Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM ...
Blum B +6 more
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Graph Theory and Networks in Biology [PDF]
, 2006 In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality measures to ...
Mason, Oliver, Verwoerd, Mark
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The effects of weather and climate change on dengue [PDF]
, 2013 There is much uncertainty about the future impact of climate change on vector-borne diseases. Such uncertainty reflects the difficulties in modelling the complex interactions between disease, climatic and socioeconomic determinants.
Colón-González, Felipe J. +3 more
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BMC Infectious Diseases, 2017 Background The international spread of wild poliomyelitis outbreaks continues to threaten eradication of poliomyelitis and in 2014 a public health emergency of international concern was declared.
Kathleen M. O’Reilly +5 more
doaj +1 more source
Molecular Autism, 2020 The complex pathophysiology of autism spectrum disorder encompasses interactions between genetic and environmental factors. On the one hand, hundreds of genes, converging at the functional level on selective biological domains such as epigenetic ...
Cristina Cheroni +2 more
doaj +1 more source
Vaccines, 2021 New tuberculosis vaccines have made substantial progress in the development pipeline. Previous modelling suggests that adolescent/adult mass vaccination may cost-effectively contribute towards achieving global tuberculosis control goals.
Chathika Krishan Weerasuriya +5 more
doaj +1 more source
Data quality predicts care quality: findings from a national clinical audit [PDF]
, 2020 Background: Missing clinical outcome data are a common occurrence in longitudinal studies. Data quality in clinical audit is a particular cause for concern. The relationship between departmental levels of missing clinical outcome data and care quality is
Bechman, Katie +6 more
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