Results 31 to 40 of about 229,289 (316)

Mathematical modelling of cancer: an ecological approach to the multiple myeloma bone disease [PDF]

, 2022
openThe insurgance of cancer disrupts the cellular environment, introducing many uncontrolled interactions within healthy tissues. It is possible, as we said, consider this process as an evolution of species where different types of cells are different ...
OTTAVI, ENIA
core  

Demonstrating multi-country calibration of a tuberculosis model using new history matching and emulation package - hmer

Epidemics, 2023
Infectious disease models are widely used by epidemiologists to improve the understanding of transmission dynamics and disease natural history, and to predict the possible effects of interventions.
Danny Scarponi, Andrew Iskauskas, Rebecca A. Clark, Ian Vernon, Trevelyan J. McKinley, Michael Goldstein, Christinah Mukandavire, Arminder Deol, Chathika Weerasuriya, Roel Bakker, Richard G. White, Nicky McCreesh   +11 more
doaj   +1 more source

Topographic determinants of foot and mouth disease transmission in the UK 2001 epidemic [PDF]

, 2006
Background A key challenge for modelling infectious disease dynamics is to understand the spatial spread of infection in real landscapes. This ideally requires a parallel record of spatial epidemic spread and a detailed map of susceptible host density ...
Savill Nicholas J, MatthewJ Keeling, Rob Deardon, Grenfell Bryan T, Shaw, Darren J; id_orcid, Savill, Nicholas J., Shaw Darren J, Deardon, Rob, Deardon Rob, Brooks, Stephan P., NicholasJ Savill, Woolhouse Mark EJ, Woolhouse, Mark E. J., Brooks, Stephen P, Grenfell, Bryan T., Keeling Matthew J, MichaelJ Tildesley, Woolhouse, Mark E J; id_orcid, BryanT Grenfell, Tildesley Michael J, Brooks Stephen P, Keeling, Matthew James, Tildesley, Michael J., Keeling, Matthew J, Tildesley, Michael J, Grenfell, Bryan T, MarkEJ Woolhouse, StephenP Brooks, Shaw, Darren J., Savill, Nicholas J, DarrenJ Shaw   +30 more
core   +1 more source

The Accuracy of 3D Optical Reconstruction and Additive Manufacturing Processes in Reproducing Detailed Subject-Specific Anatomy

Journal of Imaging, 2017
3D reconstruction and 3D printing of subject-specific anatomy is a promising technology for supporting clinicians in the visualisation of disease progression and planning for surgical intervention. In this context, the 3D model is typically obtained from
Paolo Ferraiuoli, Jonathan C. Taylor, Emily Martin, John W. Fenner, Andrew J. Narracott   +4 more
doaj   +1 more source

Data needs for integrated economic-epidemiological models of pandemic mitigation policies

Epidemics, 2022
The COVID-19 pandemic and the mitigation policies implemented in response to it have resulted in economic losses worldwide. Attempts to understand the relationship between economics and epidemiology has led to a new generation of integrated mathematical ...
David J. Haw, Christian Morgenstern, Giovanni Forchini, Rob Johnson, Patrick Doohan, Peter C. Smith, Katharina D. Hauck   +6 more
doaj   +1 more source

Fitting homocysteine to disease models, as well as adjusting the models to the disease [PDF]

Journal of Molecular Medicine, 2015
Homocysteine is a nonprotein α-amino acid and differs from cysteine by having an additional methylene bridge. Homocysteine is not present in the diet, and all homocysteine in the body is biosynthesized from the essential amino acid methionine. Homocysteine is a product of methionine demethylation and is recycled into methionine or alternatively ...
openaire   +2 more sources

Evaluation of Models of Parkinson's Disease [PDF]

Frontiers in Neuroscience, 2016
Parkinson's disease is one of the most common neurodegenerative diseases. Animal models have contributed a large part to our understanding and therapeutics developed for treatment of PD. There are several more exhaustive reviews of literature that provide the initiated insights into the specific models; however a novel synthesis of the basic advantages
Jagmag, Shail A., Tripathi, Naveen, Shukla, Sunil D., Maiti, Sankar, Khurana, Sukant   +4 more
openaire   +3 more sources

Stochastic modelling of the spatial spread of influenza in Germany [PDF]

, 2005
In geographical epidemiology, disease counts are typically available in discrete spatial units and at discrete time-points. For example, surveillance data on infectious diseases usually consists of weekly counts of new infections in pre-defined ...
Dargatz, C, Held, Leonhard, Georgescu, Vera, Georgescu, V, Held, L, Dargatz, Christiane ; https://orcid.org/, Dargatz, Christiane   +6 more
core   +1 more source

Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts

The Lancet Global Health, 2020
Summary: Background: Isolation of cases and contact tracing is used to control outbreaks of infectious diseases, and has been used for coronavirus disease 2019 (COVID-19). Whether this strategy will achieve control depends on characteristics of both the
Joel Hellewell, PhD, Sam Abbott, PhD, Amy Gimma, MSc, Nikos I Bosse, BSc, Christopher I Jarvis, PhD, Timothy W Russell, PhD, James D Munday, MSc, Adam J Kucharski, PhD, W John Edmunds, ProfPhD, Sebastian Funk, PhD, Rosalind M Eggo, PhD, Fiona Sun, Stefan Flasche, Billy J Quilty, Nicholas Davies, Yang Liu, Samuel Clifford, Petra Klepac, Mark Jit, Charlie Diamond, Hamish Gibbs, Kevin van Zandvoort   +21 more
doaj   +1 more source

Bayesian spatiotemporal modelling of chronic disease outcomes

, 2017
This thesis contributes to Bayesian spatial and spatiotemporal methodology by investigating techniques for spatial imputation and joint disease modelling, and identifies high-risk individual profiles and geographic areas for type II diabetes mellitus ...
Baker, Jannah F.
core   +1 more source