Results 21 to 30 of about 229,289 (316)

Quantifying the impact of physical distance measures on the transmission of COVID-19 in the UK

open access: yesBMC Medicine, 2020
Background To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether these measures might be sufficient to control the epidemic by estimating their impact on
Christopher I. Jarvis   +7 more
doaj   +1 more source

Perspective: A model disease [PDF]

open access: yesNature, 2011
Despite its rarity, multiple myeloma is an ideal testing ground for cancer biology, says William Matsui.
openaire   +2 more sources

Spatio-temporal epidemic modelling using additive-multiplicative intensity models [PDF]

open access: yes, 2008
An extension of the stochastic susceptible-infectious-recovered (SIR) model is proposed in order to accommodate a regression context for modelling infectious disease surveillance data. The proposal is based on a multivariate counting process specified by
Höhle, Michael
core   +1 more source

Risk of foot-and-mouth disease spread due to sole occupancy authorities and linked cattle holdings [PDF]

open access: yes, 2012
Livestock movements in Great Britain are well recorded, have been extensively analysed with respect to their role in disease spread, and have been used in real time to advise governments on the control of infectious diseases.
O'Hare, Anthony   +27 more
core   +1 more source

Cellular models of Batten disease

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2020
The Neuronal Ceroid Lipofuscinoses (NCL), otherwise known as Batten disease, are a group of neurodegenerative diseases caused by mutations in 13 known genes. All except one NCL is autosomal recessive in inheritance, with similar aetiology and characterised by the accumulation of autofluorescent storage material in the lysosomes of cells.
Minnis, CJ   +3 more
openaire   +3 more sources

Parathyroid Diseases and Animal Models [PDF]

open access: yesFrontiers in Endocrinology, 2012
CIRCULATING CALCIUM AND PHOSPHATE ARE TIGHTLY REGULATED BY THREE HORMONES: the active form of vitamin D (1,25-dihydroxyvitamin D), fibroblast growth factor (FGF)-23, and parathyroid hormone (PTH). PTH acts to stimulate a rapid increment in serum calcium and has a crucial role in calcium homeostasis. Major target organs of PTH are kidney and bone.
Imanishi, Yasuo   +2 more
openaire   +3 more sources

Caprine arthritis encephalitis virus disease modelling review [PDF]

open access: yes, 2021
Mathematical modelling is used in disease studies to assess the economical impacts of diseases, as well as to better understand the epidemiological dynamics of the biological and environmental factors that are associated with disease spreading.
Brotto Rebuli, K.   +5 more
core   +1 more source

An assessment of the geographical risks of wild and vaccine-derived poliomyelitis outbreaks in Africa and Asia

open access: yesBMC Infectious Diseases, 2017
Background The international spread of wild poliomyelitis outbreaks continues to threaten eradication of poliomyelitis and in 2014 a public health emergency of international concern was declared.
Kathleen M. O’Reilly   +5 more
doaj   +1 more source

Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology

open access: yesMolecular Autism, 2020
The complex pathophysiology of autism spectrum disorder encompasses interactions between genetic and environmental factors. On the one hand, hundreds of genes, converging at the functional level on selective biological domains such as epigenetic ...
Cristina Cheroni   +2 more
doaj   +1 more source

Affordability of Adult Tuberculosis Vaccination in India and China: A Dynamic Transmission Model-Based Analysis

open access: yesVaccines, 2021
New tuberculosis vaccines have made substantial progress in the development pipeline. Previous modelling suggests that adolescent/adult mass vaccination may cost-effectively contribute towards achieving global tuberculosis control goals.
Chathika Krishan Weerasuriya   +5 more
doaj   +1 more source

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