Results 21 to 30 of about 666,620 (307)

Simulating Drug-Eluting Stents: Progress Made and the Way Forward [PDF]

open access: yes, 2013
Drug-eluting stents have significantly improved the treatment of coronary artery disease. Compared with their bare metal predecessors, they offer reduced rates of restenosis and thus represent the current gold standard in percutaneous coronary ...
Kennedy, Simon   +5 more
core   +2 more sources

Control of mosaic disease using microbial biostimulants: insights from mathematical modelling [PDF]

open access: yes, 2020
A major challenge to successful crop production comes from viral diseases of plants that cause significant crop losses, threatening global food security and the livelihoods of countries that rely on those crops for their staple foods or source of income.
Al Basir, Fahad   +8 more
core   +1 more source

Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD. [PDF]

open access: yes, 2017
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and a leading cause of mortality and morbidity worldwide. The aim of this study was to investigate the sex dependency of circulating metabolic profiles in COPD.Serum from healthy ...
Erle, David J   +11 more
core   +1 more source

Zebrafish Models of Cerebrovascular Disease [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 2014
Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a heterogeneous group of disease processes, the ultimate final pathologic insult in humans is defined as a stroke, or damage to brain ...
Walcott, Brian, Peterson, Randall
openaire   +3 more sources

Cost-effectiveness of routine adolescent vaccination with an M72/AS01E-like tuberculosis vaccine in South Africa and India

open access: yesNature Communications, 2022
The M72/AS01E tuberculosis vaccine has shown 50% efficacy in preventing pulmonary TB disease in infected 18–50 year olds. Here, the authors demonstrate that, in most scenarios modelled, vaccination of adolescents would also be cost effective in two high ...
Rebecca C. Harris   +6 more
doaj   +1 more source

A space-time conditional intensity model for infectious disease occurence [PDF]

open access: yes, 2010
A novel point process model continuous in space-time is proposed for infectious disease data. Modelling is based on the conditional intensity function (CIF) and extends an additive-multiplicative CIF model previously proposed for discrete space epidemic ...
Assunçáo   +26 more
core   +3 more sources

Quantifying the impact of physical distance measures on the transmission of COVID-19 in the UK

open access: yesBMC Medicine, 2020
Background To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether these measures might be sufficient to control the epidemic by estimating their impact on
Christopher I. Jarvis   +7 more
doaj   +1 more source

Bayesian Modelling of Inseparable Space-Time Variation in Disease Risk [PDF]

open access: yes, 1998
This paper proposes a unified framework for a Bayesian analysis of incidence or mortality data in space and time. We introduce four different types of prior distributions for space $\times$ time interaction in extension of a model with only main effects.
Knorr-Held, Leonhard
core   +4 more sources

Perspective: A model disease [PDF]

open access: yesNature, 2011
Despite its rarity, multiple myeloma is an ideal testing ground for cancer biology, says William Matsui.
openaire   +2 more sources

The effects of weather and climate change on dengue [PDF]

open access: yes, 2013
There is much uncertainty about the future impact of climate change on vector-borne diseases. Such uncertainty reflects the difficulties in modelling the complex interactions between disease, climatic and socioeconomic determinants.
Colón-González, Felipe J.   +3 more
core   +2 more sources

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