Results 41 to 50 of about 666,620 (307)
Journal of Imaging, 2017 3D reconstruction and 3D printing of subject-specific anatomy is a promising technology for supporting clinicians in the visualisation of disease progression and planning for surgical intervention. In this context, the 3D model is typically obtained from
Paolo Ferraiuoli +4 more
doaj +1 more source
Fitting homocysteine to disease models, as well as adjusting the models to the disease [PDF]
Journal of Molecular Medicine, 2015 Homocysteine is a nonprotein α-amino acid and differs from cysteine by having an additional methylene bridge. Homocysteine is not present in the diet, and all homocysteine in the body is biosynthesized from the essential amino acid methionine. Homocysteine is a product of methionine demethylation and is recycled into methionine or alternatively ...
openaire +2 more sources
Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts
The Lancet Global Health, 2020 Summary: Background: Isolation of cases and contact tracing is used to control outbreaks of infectious diseases, and has been used for coronavirus disease 2019 (COVID-19). Whether this strategy will achieve control depends on characteristics of both the
Joel Hellewell, PhD +21 more
doaj +1 more source
Use of evidence to support healthy public policy: a policy effectiveness-feasibility loop [PDF]
, 2012 Public policy plays a key role in improving population health and in the control of diseases, including non-communicable diseases. However, an evidence-based approach to formulating healthy public policy has been difficult to implement, partly on ...
Ahmad, B +13 more
core +2 more sources
Combined population dynamics and entropy modelling supports patient stratification in chronic myeloid leukemia [PDF]
, 2016 Modelling the parameters of multistep carcinogenesis is key for a better understanding of cancer progression, biomarker identification and the design of individualized therapies.
Brehme, Marc +7 more
core +1 more source
The Lancet Global Health, 2016 Background: Reducing the burden of malaria is a global priority, but financial constraints mean that available resources must be allocated rationally to maximise their effect.
Dr. Patrick G T Walker, PhD +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
outbreaker2: a modular platform for outbreak reconstruction
BMC Bioinformatics, 2018 Background Reconstructing individual transmission events in an infectious disease outbreak can provide valuable information and help inform infection control policy.
Finlay Campbell +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Nature CommunicationsSARS-CoV-2 continues to cause substantial morbidity and mortality, particularly in winter. During the SARS-CoV-2 pandemic, community prevalence surveys provided detailed monitoring of infection levels.
Martyn Fyles +6 more
doaj +1 more source