Results 51 to 60 of about 666,620 (307)

A hybrid CA-PDE Model of chlamydia trachomatis infection in the female genital tract [PDF]

, 2008
Chlamydia trachomatis is amongst the most common sexually transmitted diseases in the world and when left untreated, may lead to serious sequelae particularly in women such as pelvic inflammatory disease, ectopic pregnancy and infertility. Currently, most
Heymer, Kelly-Jean, Mallet, Daniel G., Wilson, David P.   +2 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

The epidemiologic impact and cost-effectiveness of new tuberculosis vaccines on multidrug-resistant tuberculosis in India and China

BMC Medicine, 2021
Background Despite recent advances through the development pipeline, how novel tuberculosis (TB) vaccines might affect rifampicin-resistant and multidrug-resistant tuberculosis (RR/MDR-TB) is unknown.
Chathika K Weerasuriya, Rebecca C Harris, C Finn McQuaid, Fiammetta Bozzani, Yunzhou Ruan, Renzhong Li, Tao Li, Kirankumar Rade, Raghuram Rao, Ann M Ginsberg, Gabriela B Gomez, Richard G White   +11 more
doaj   +1 more source

Disease modelling using evolved discriminate function [PDF]

, 2003
Precocious diagnosis increases the survival time and patient quality of life. It is a binary classification, exhaustively studied in the literature. This paper innovates proposing the application of genetic programming to obtain a discriminate function ...
Kalganova, T, Werner, J C
core  

Predicting Distribution of Aedes Aegypti and Culex Pipiens Complex, Potential Vectors of Rift Valley Fever Virus in Relation to Disease Epidemics in East Africa. [PDF]

, 2013
The East African region has experienced several Rift Valley fever (RVF) outbreaks since the 1930s. The objective of this study was to identify distributions of potential disease vectors in relation to disease epidemics.
Abdo-Salem S, Amraoui F, Anyamba A, Anyangu AS, Aradaib IE, Clements AC, Crabtree MB, Dar O, Daubney R, Diallo M, EFSA Panel on Animal Health and Welfare, Gerdes GH, Jost CC, Jupp PG, Kebede S, Kija B, Kitau J, Le GG, Linthicum KJ, Linthicum KJ, Lobo JM, Logan TM, Logan TM, Meegan JM, Mohamed M, Montesinos-Lopez OA, Moutailler S, Nguku PM, Ogoma SB, Ortega-Huerta M, Pearson RG, Pearson RG, Peterson AT, Phillips SJ, Rweyemamu M, Sang R, Swets JA, Tabachnick WJ, Turell MJ, Warren DL, Wisz MS   +40 more
core   +2 more sources

Data quality predicts care quality: findings from a national clinical audit [PDF]

, 2020
Background: Missing clinical outcome data are a common occurrence in longitudinal studies. Data quality in clinical audit is a particular cause for concern. The relationship between departmental levels of missing clinical outcome data and care quality is
Bechman, Katie, Dennison, Elaine M., Galloway, James B., Ledingham, Jo, Macgregor, Alexander J., Norton, Sam, Yates, Mark   +6 more
core   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

COMET-LF: a compartmental model of dynamics of infection, disease, and elimination strategies for lymphatic filariasis

BMC Infectious Diseases
Background Lymphatic filariasis (LF) is a mosquito-borne disease caused by filarial worms. The WHO has targeted LF elimination by 2030. Mathematical models can help evaluate and guide elimination strategies. Methods We developed a new compartmental model—
Indrajit Ghosh, Suchita Nath-Sain, Shoummo Sen Gupta, Chhavi Pant Joshi, Tanu Jain, Swaminathan Subramanian, Souvik Banerjee, Mithun K. Mitra   +7 more
doaj   +1 more source

Modelling the benefits of long-acting or transmission-blocking drugs for reducing Plasmodium falciparum transmission by case management or by mass treatment

Malaria Journal, 2017
Background Anti-malarial drugs are an important tool for malaria control and elimination. Alongside their direct benefit in the treatment of disease, drug use has a community-level effect, clearing the reservoir of infection and reducing onward ...
Michael T. Bretscher, Jamie T. Griffin, Azra C. Ghani, Lucy C. Okell   +3 more
doaj   +1 more source