Results 11 to 20 of about 229,289 (316)
The potential impact of programmes interruptions due to COVID-19 on 7 neglected tropical diseases: a modelling-based analysis [PDF]
, 2020 The spread of SARS-CoV-2 (COVID-19) will impact the progress of neglected tropical disease (NTD) programmes. In the short term, World Health Organization (WHO) guidance advises that many NTD surveys, active case finding activities, and mass drug ...
Modelling Consortium, NTD
core +1 more source
Brain network, modelling and corresponding EEG patterns for health and disease states [PDF]
, 2020 EEG is a significant tool used to capture normal and abnormal cerebral electrical activities in human brain. To understand and test complex hypotheses about the mechanisms of their generation, various model and modelling approaches have been proposed and
Al-Hossenat, Auhood Hadi Jabbar
core +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2020 Gaucher’s disease type 1 (GD1) leads to significant morbidity and mortality through clinical manifestations, such as splenomegaly, hematological complications, and bone disease.
Ruth Abrams +15 more
doaj +1 more source
BMC Medicine, 2021 Background England’s COVID-19 response transitioned from a national lockdown to localised interventions. In response to rising cases, these were supplemented by national restrictions on contacts (the Rule of Six), then 10 pm closing for bars and ...
Christopher I. Jarvis +5 more
doaj +1 more source
Response strategies for COVID-19 epidemics in African settings: a mathematical modelling study
BMC Medicine, 2020 Background The health impact of COVID-19 may differ in African settings as compared to countries in Europe or China due to demographic, epidemiological, environmental and socio-economic factors.
Kevin van Zandvoort +11 more
doaj +1 more source
Multiscale modeling in disease
Current Opinion in Systems Biology, 2021 Multiscale computational modeling aims to connect the complex networks of effects at different length and/or time scales. For example, these networks often include intracellular molecular signaling, crosstalk, and other interactions between neighboring cell populations, and higher levels of emergent phenomena across different regions of tissues and ...
openaire +2 more sources
Animal Models of Human Disease
International Journal of Molecular Sciences, 2023 The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic entitled “Animal Models of Human Disease” aimed to collect state-of-the-art primary research studies and review articles from international ...
Lange, Sigrun, Inal, Jameel
openaire +3 more sources
A space-time conditional intensity model for infectious disease occurence [PDF]
, 2010 A novel point process model continuous in space-time is proposed for infectious disease data. Modelling is based on the conditional intensity function (CIF) and extends an additive-multiplicative CIF model previously proposed for discrete space epidemic ...
Höhle, Michael +5 more
core +1 more source
Nature Communications, 2022 The M72/AS01E tuberculosis vaccine has shown 50% efficacy in preventing pulmonary TB disease in infected 18–50 year olds. Here, the authors demonstrate that, in most scenarios modelled, vaccination of adolescents would also be cost effective in two high ...
Rebecca C. Harris +6 more
doaj +1 more source
Zebrafish Models of Cerebrovascular Disease [PDF]
Journal of Cerebral Blood Flow & Metabolism, 2014 Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a heterogeneous group of disease processes, the ultimate final pathologic insult in humans is defined as a stroke, or damage to brain ...
Walcott, Brian, Peterson, Randall
openaire +4 more sources