Results 41 to 50 of about 659,696 (286)
Statistical Disease Progression Modeling in Alzheimer Disease [PDF]
Frontiers in Big Data, 2020 Background: The characterizing symptom of Alzheimer disease (AD) is cognitive deterioration. While much recent work has focused on defining AD as a biological construct, most patients are still diagnosed, staged, and treated based on their cognitive symptoms.
Lars Lau Raket, Lars Lau Raket
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski +59 more
wiley +1 more source
outbreaker2: a modular platform for outbreak reconstruction
BMC Bioinformatics, 2018 Background Reconstructing individual transmission events in an infectious disease outbreak can provide valuable information and help inform infection control policy.
Finlay Campbell +5 more
doaj +1 more source
Looking Back: Disease Modeling [PDF]
Cell Stem Cell, 2017 Over the past decade, the growth of stem cell-based models of human disorders has contributed to novel drug discovery and precision medicine possibilities. For our tenth anniversary, we asked authors who cited a selection of our most popular papers in this area about how these studies influenced them.
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Disease modelling using evolved discriminate function [PDF]
, 2003 Precocious diagnosis increases the survival time and patient quality of life. It is a binary classification, exhaustively studied in the literature. This paper innovates proposing the application of genetic programming to obtain a discriminate function ...
Kalganova, T, Werner, J C
core
Computational Modelling of Atherosclerosis
, 2015 Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk from elevated ...
Baldrick, Francina R +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware +13 more
wiley +1 more source
Nature CommunicationsSARS-CoV-2 continues to cause substantial morbidity and mortality, particularly in winter. During the SARS-CoV-2 pandemic, community prevalence surveys provided detailed monitoring of infection levels.
Martyn Fyles +6 more
doaj +1 more source
Dynamics of COVID-19 epidemics: SEIR models underestimate peak infection rates and overestimate epidemic duration [PDF]
, 2020 Compartment models of infectious diseases, such as SEIR, are being used extensively to model the COVID-19 epidemic. Transitions between compartments are modelled either as instantaneous rates in differential equations, or as transition probabilities in ...
Grant, Alastair
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark +9 more
wiley +1 more source