Results 241 to 250 of about 1,875,199 (316)

Circadian Rhythm Dysfunction in Neurodegenerative Diseases: A Bidirectional Perspective and Therapeutic Potential. [PDF]

Nat Sci Sleep
Namgyal D, Lim CS.
europepmc   +1 more source

Animal Model of Disease [PDF]

, 2020
openaire   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Investigate the differences in executive functions and behavioral baseline indicators of Parkinson's disease model mice based on the five - choice serial reaction time task. [PDF]

Lab Anim Res
Gu H, Liao Z, Zhou Z, Liu Z, Gu M, Liang X, Pan H, Tang C.   +7 more
europepmc   +1 more source

Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank, Benjamin M. Jacobs, Jonathan Bestwick, Ruth Dobson   +3 more
wiley   +1 more source

Bioengineered Humanoid-on-Chip Platforms: Tools for Evaluating the Effects of Environmental Exposure on Human Physiological Barriers. [PDF]

Thorac Res Pract
Saglam-Metiner P, Goksel O, Goksel T, Yilmaz OH, Erdal E, Yesil-Celiktas O.   +5 more
europepmc   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Reply to "Investigating a role for NSAIDs in the pathophysiology of vaccine-associated myocarditis". [PDF]

NPJ Vaccines
Buoninfante A, Cavaleri M.
europepmc   +1 more source

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu, Yongsheng Wu, Junyu Qu, Rui Zhu, Wenwen Xu, Jiaxiang Xin, Dawei Wang   +6 more
wiley   +1 more source

Spatiotemporal Distribution and Meteorological Determinants of Lumpy Skin Disease (LSD) Occurrence in Bangladesh From 2020 to 2023. [PDF]

Transbound Emerg Dis
Ahmed MJ, Alam KE, Talukdar F, Bhuiyan MIH, Bhandari P, Chalise R, Mahamud D, Hossain MI, Sabrin MS, Chowdhury MTI, Alam MJ, Hossain D.   +11 more
europepmc   +1 more source