Results 261 to 270 of about 1,875,199 (316)

Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies. [PDF]

Front Pharmacol
Lv Z, Pan Z, Huang Y, Yang H, Li X.
europepmc   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

From Cells to Organoids: Approaches, Regulatory Mechanisms, Applications, and Challenges of Organoids. [PDF]

Cells
Wang L, Chen A, Zhang D, He Z.
europepmc   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

Artificial intelligence-, organoid-, and organ-on-chip-powered models to improve pre-clinical animal testing of vaccines and immunotherapeutics: potential, progress, and challenges. [PDF]

Front Artif Intell
Elfatimi E, Lekbach Y, Prakash S, Karan S, Dorotta JC, Garcia A, Suoth BS, Maurya C, Omorogieva EY, Ng SXL, Liao EJ, Chow RA, BenMohamed L.   +12 more
europepmc   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Animal Models of Narcolepsy: From Orexin Deficiency to Immune Mechanisms and Regenerative Therapies. [PDF]

Curr Issues Mol Biol
Arias-Carrión O, Ortega-Robles E.
europepmc   +1 more source

Development of convolutional neural networks for automated brain-wide histopathological analysis in mouse models of synucleinopathies. [PDF]

NPJ Parkinsons Dis
Barber-Janer A, Van Acker E, Vonck E, Plessers D, Rosada F, Van den Haute C, Baekelandt V, Peelaerts W.   +7 more
europepmc   +1 more source

Is Sexual Transmission of Chagas Disease Possible? Evaluating the Evidence and Future Directions. [PDF]

Pathogens
De Jesús-González LA, Martínez I, Espinoza B, Lira-Hernández FI.   +3 more
europepmc   +1 more source

Human-Based Technologies in Cardiovascular Pharmacology Research. [PDF]

J Cardiovasc Pharmacol
Biondi-Zoccai G, Frati G, Carnevale R, Booz GW.   +3 more
europepmc   +1 more source