Results 281 to 290 of about 1,875,199 (316)

Animal Models of Nonthyroidal Disease*

Endocrine Reviews, 1985
Rats bearing transplantable Walker 256 carcinoma provide an opportunity to assess thyroid function and activity during an interval of time when the tumor has not affected growth rate. Rats with tumor have decreased serum T4 and T3 concentration and decreased serum FT4 and FT3 as well.
J M, Tibaldi, M I, Surks
openaire   +2 more sources

Animal Models for Meningococcal Disease

2003
There are many in vitro systems for the study of meningococcal pathogenesis, but it is only in animal models of infection that the interactions of the bacteria with whole tissues and the humoral and cellular immune systems can be assessed. Animal-infection models are also of great importance for the assessment of the protective efficacy of existing and
A R, Gorringe, K M, Reddin, P, Voet, J T, Poolman   +3 more
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Animal Models of Cardiovascular Disease

Revista Española de Cardiología (English Edition), 2009
The use of animal models to study cardiovascular disease has made a substantial contribution to increasing our understanding of disease pathogenesis, has led to the development of diagnostic techniques, and has made it possible to verify the effectiveness of different preventative and therapeutic approaches, whether pharmacological or interventional ...
Francisco J, Chorro, Luis, Such-Belenguer, Vicente, López-Merino   +2 more
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Parkinson's disease: animal models

2007
Publisher Summary Animal models are an essential tool to study human diseases, not only to enable a thorough investigation into the mechanisms involved in the pathogenesis of a disease but also to help in the development of therapeutic strategies. This chapter describes genetic as well as pharmacological manipulations used to develop animal models ...
Ranjita, Betarbet, J Timothy, Greenamyre
openaire   +2 more sources

Animal Models of Retinal Disease

2011
Diseases of the retina are the leading causes of blindness in the industrialized world. The recognition that animals develop retinal diseases with similar traits to humans has led to not only a dramatic improvement in our understanding of the pathogenesis of retinal disease but also provided a means for testing possible treatment regimes and successful
Erica L, Fletcher, Andrew I, Jobling, Kirstan A, Vessey, Chi, Luu, Robyn H, Guymer, Paul N, Baird   +5 more
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Animal Models for Mitochondrial Disease

2003
Mutations in mitochondrial genes encoded by both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA have been implicated in a wide range of degenerative diseases. MtDNA base substitution and rearrangement mutations can cause myopathy, cardiomyopathy, ophthalmological defects, growth retardation, movement disorders, dementias, and diabetes.
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Animal Models of Menkes Disease

1999
There are three recognized X-linked copper deficiency disorders in humans: classical Menkes disease (MD), mild Menkes disease and occipital horn syndrome (OHS, also known as X-linked cutis laxa). Since the features of these diseases are so distinct, it was not clear until recently whether the phenotypes were due to mutations in the same gene, or ...
J F, Mercer, L, Ambrosini, S, Horton, S, Gazeas, A, Grimes   +4 more
openaire   +2 more sources

Animal models of disease

Physiology & Behavior, 2000
P M, McCabe, J F, Sheridan, J M, Weiss, J P, Kaplan, B H, Natelson, W P, Pare   +5 more
openaire   +2 more sources

Animal models in human disease

PROTEOMICS – Clinical Applications, 2008
Claus, Zabel, Joachim, Klose
openaire   +2 more sources

Molecular imaging in oncology: Current impact and future directions

Ca-A Cancer Journal for Clinicians, 2022
Steven P Rowe, Martin G Pomper
exaly