Results 1 to 10 of about 2,922,586 (338)

Surveillance of the progression and assessment of treatment endpoints for nonalcoholic steatohepatitis [PDF]

Clinical and Molecular Hepatology, 2023
Nonalcoholic steatohepatitis (NASH) is an aggressive form of nonalcoholic fatty liver disease (NAFLD) characterized by steatosis-associated inflammation and liver injury. Without effective treatment or management, NASH can have life-threatening outcomes.
Yi-wen Shi, Jian-Gao Fan
doaj   +1 more source

A Comparative Retrospective Study of Immunotherapy RANO Versus Standard RANO Criteria in Glioblastoma Patients Receiving Immune Checkpoint Inhibitor Therapy

Frontiers in Oncology, 2021
ObjectivesReal-time assessment of treatment response in glioblastoma (GBM) patients on immune checkpoint blockade (ICB) remains challenging because inflammatory effects of therapy may mimic progressive disease, and the temporal evolution of these ...
Xin Chen, Xin Chen, Mary Jane Lim-Fat, Lei Qin, Lei Qin, Angie Li, Angie Li, Annie Bryant, Camden P. Bay, Lu Gao, Lu Gao, Nityanand Miskin, Nityanand Miskin, Zaiyi Liu, J. Bryan Iorgulescu, Xiaoyin Xu, Xiaoyin Xu, David A. Reardon, David A. Reardon, Geoffrey S. Young, Geoffrey S. Young, Geoffrey S. Young   +21 more
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Leflunomide plus low-dose prednisone in patients with progressive IgA nephropathy: a multicenter, prospective, randomized, open-labeled, and controlled trial

Renal Failure, 2021
Background Immunoglobulin A nephropathy (IgAN) is the most common cause of glomerulonephritis worldwide, and the optimal approach to its treatment remains a significant challenge.
Zhaohui Ni, Zhen Zhang, Zanzhe Yu, Fuming Lu, Changlin Mei, Xiaoqiang Ding, Weijie Yuan, Wei Zhang, Gengru Jiang, Min Sun, Liqun He, Yueyi Deng, Huihua Pang, Jiaqi Qian   +13 more
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Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients

Frontiers in Neurology, 2021
Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based patients with incident PD ...
Aleksandra A. Szwedo, Aleksandra A. Szwedo, Camilla Christina Pedersen, Camilla Christina Pedersen, Anastasia Ushakova, Lars Forsgren, Ole-Bjørn Tysnes, Ole-Bjørn Tysnes, Carl E. Counsell, Guido Alves, Guido Alves, Guido Alves, Johannes Lange, Johannes Lange, Angus D. Macleod, Jodi Maple-Grødem, Jodi Maple-Grødem   +16 more
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Learning Progression: How should we teach about disease to determine students’ level of understanding?

JPBI (Jurnal Pendidikan Biologi Indonesia), 2021
Strengthening Learning Progression (LP) for students' reasoning abilities is important, especially learning about diseases in Indonesia. This study aimed to map the learning progression of disease in Indonesia, compare and analyze its similarities and ...
Roni Ardiansyah, H. Harlita, Murni Ramli
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Cytokine/Chemokine Expression Is Closely Associated Disease Severity of Human Adenovirus Infections in Immunocompetent Adults and Predicts Disease Progression

Frontiers in Immunology, 2021
Increasing human Adenovirus (HAdV) infections complicated with acute respiratory distress syndrome (ARDS) even fatal outcome were reported in immunocompetent adolescent and adult patients. Here, we characterized the cytokine/chemokine expression profiles
Jin Li, Jinli Wei, Zhixiang Xu, Chunmei Jiang, Mianhuan Li, Jie Chen, Yanjie Li, Minghui Yang, Yuchen Gu, Fuxiang Wang, Yuelong Shu, Yang Yang, Litao Sun, Yingxia Liu   +13 more
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Facts and Gaps in Exercise Influence on Arrhythmogenic Cardiomyopathy: New Insights From a Meta-Analysis Approach

Frontiers in Cardiovascular Medicine, 2021
Arrhythmogenic cardiomyopathy (ACM) is a genetic cardiac condition characterized by fibrofatty myocardial replacement, either at the right ventricle, at the left ventricle, or with biventricular involvement.
Julia Martínez-Solé, María Sabater-Molina, María Sabater-Molina, María Sabater-Molina, Aitana Braza-Boïls, Aitana Braza-Boïls, Juan J. Santos-Mateo, Pilar Molina, Pilar Molina, Luis Martínez-Dolz, Luis Martínez-Dolz, Juan R. Gimeno, Juan R. Gimeno, Juan R. Gimeno, Esther Zorio, Esther Zorio, Esther Zorio   +16 more
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Oral Feeding of an Antioxidant Cocktail as a Therapeutic Strategy in a Mouse Model of Rett Syndrome: Merits and Limitations of Long-Term Treatment

Antioxidants, 2022
Rett syndrome (RTT) is a severe neurodevelopmental disorder that typically arises from spontaneous germline mutations in the X-chromosomal methyl-CpG binding protein 2 (MECP2) gene.
Laura Baroncelli, Stefanie Auel, Lena Rinne, Ann-Kathrin Schuster, Victoria Brand, Belinda Kempkes, Katharina Dietrich, Michael Müller   +7 more
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Genome-wide studies in prostate cancer poised liquid biopsy as a molecular discovery tool

Frontiers in Oncology, 2023
Liquid biopsy is emerging as an intriguing tool in clinical disease detection and monitoring. Compared to a standard tissue biopsy, performing a liquid biopsy incurs minimal invasiveness, captures comprehensive disease representation, and can be more ...
Nicholas Lo, Housheng Hansen He, Housheng Hansen He, Sujun Chen, Sujun Chen   +4 more
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Data-Driven Sequence of Changes to Anatomical Brain Connectivity in Sporadic Alzheimer’s Disease

Frontiers in Neurology, 2017
Model-based investigations of transneuronal spreading mechanisms in neurodegenerative diseases relate the pattern of pathology severity to the brain’s connectivity matrix, which reveals information about how pathology propagates through the connectivity ...
Neil P. Oxtoby, Sara Garbarino, Nicholas C. Firth, Nicholas C. Firth, Jason D. Warren, Jonathan M. Schott, Daniel C. Alexander, For the Alzheimer’s Disease Neuroimaging Initiative   +7 more
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