Results 1 to 10 of about 12,789,497 (387)

Surveillance of the progression and assessment of treatment endpoints for nonalcoholic steatohepatitis [PDF]

Clinical and Molecular Hepatology, 2023
Nonalcoholic steatohepatitis (NASH) is an aggressive form of nonalcoholic fatty liver disease (NAFLD) characterized by steatosis-associated inflammation and liver injury. Without effective treatment or management, NASH can have life-threatening outcomes.
Yi-wen Shi, Jian-Gao Fan
doaj   +1 more source

Wnt signaling in lung development, regeneration, and disease progression

Communications Biology, 2021
The respiratory tract is a vital, intricate system for several important biological processes including mucociliary clearance, airway conductance, and gas exchange.
Cody J. Aros, Carla J. Pantoja, B. Gomperts   +2 more
semanticscholar   +1 more source

COVID-19 outbreak in Italy: experimental chest X-ray scoring system for quantifying and monitoring disease progression

La radiologia medica, 2020
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new virus recently isolated from humans. SARS-CoV-2 was discovered to be the pathogen responsible for a cluster of pneumonia cases associated with severe respiratory disease that occurred ...
A. Borghesi, R. Maroldi
semanticscholar   +1 more source

Alzheimer’s Disease: Epidemiology and Clinical Progression

Neurological Therapeutics, 2022
Alzheimer’s disease (AD) is prevalent throughout the world and is the leading cause of dementia in older individuals (aged ≥ 65 years). To gain a deeper understanding of the recent literature on the epidemiology of AD and its progression, we conducted a ...
A. A. Tahami Monfared, M. J. Byrnes, L. White, Quanwu Zhang   +3 more
semanticscholar   +1 more source

A Comparative Retrospective Study of Immunotherapy RANO Versus Standard RANO Criteria in Glioblastoma Patients Receiving Immune Checkpoint Inhibitor Therapy

Frontiers in Oncology, 2021
ObjectivesReal-time assessment of treatment response in glioblastoma (GBM) patients on immune checkpoint blockade (ICB) remains challenging because inflammatory effects of therapy may mimic progressive disease, and the temporal evolution of these ...
Xin Chen, Xin Chen, Mary Jane Lim-Fat, Lei Qin, Lei Qin, Angie Li, Angie Li, Annie Bryant, Camden P. Bay, Lu Gao, Lu Gao, Nityanand Miskin, Nityanand Miskin, Zaiyi Liu, J. Bryan Iorgulescu, Xiaoyin Xu, Xiaoyin Xu, David A. Reardon, David A. Reardon, Geoffrey S. Young, Geoffrey S. Young, Geoffrey S. Young   +21 more
doaj   +1 more source

Biomarkers associated with COVID-19 disease progression

Critical reviews in clinical laboratory sciences, 2020
The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is centered on the unpredictable clinical course of the disease that can ...
G. Ponti, M. Maccaferri, C. Ruini, A. Tomasi, T. Ozben   +4 more
semanticscholar   +1 more source

Leflunomide plus low-dose prednisone in patients with progressive IgA nephropathy: a multicenter, prospective, randomized, open-labeled, and controlled trial

Renal Failure, 2021
Background Immunoglobulin A nephropathy (IgAN) is the most common cause of glomerulonephritis worldwide, and the optimal approach to its treatment remains a significant challenge.
Zhaohui Ni, Zhen Zhang, Zanzhe Yu, Fuming Lu, Changlin Mei, Xiaoqiang Ding, Weijie Yuan, Wei Zhang, Gengru Jiang, Min Sun, Liqun He, Yueyi Deng, Huihua Pang, Jiaqi Qian   +13 more
doaj   +1 more source

Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients

Frontiers in Neurology, 2021
Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based patients with incident PD ...
Aleksandra A. Szwedo, Aleksandra A. Szwedo, Camilla Christina Pedersen, Camilla Christina Pedersen, Anastasia Ushakova, Lars Forsgren, Ole-Bjørn Tysnes, Ole-Bjørn Tysnes, Carl E. Counsell, Guido Alves, Guido Alves, Guido Alves, Johannes Lange, Johannes Lange, Angus D. Macleod, Jodi Maple-Grødem, Jodi Maple-Grødem   +16 more
doaj   +1 more source

Learning Progression: How should we teach about disease to determine students’ level of understanding?

JPBI (Jurnal Pendidikan Biologi Indonesia), 2021
Strengthening Learning Progression (LP) for students' reasoning abilities is important, especially learning about diseases in Indonesia. This study aimed to map the learning progression of disease in Indonesia, compare and analyze its similarities and ...
Roni Ardiansyah, H. Harlita, Murni Ramli
doaj   +1 more source

Cytokine/Chemokine Expression Is Closely Associated Disease Severity of Human Adenovirus Infections in Immunocompetent Adults and Predicts Disease Progression

Frontiers in Immunology, 2021
Increasing human Adenovirus (HAdV) infections complicated with acute respiratory distress syndrome (ARDS) even fatal outcome were reported in immunocompetent adolescent and adult patients. Here, we characterized the cytokine/chemokine expression profiles
Jin Li, Jinli Wei, Zhixiang Xu, Chunmei Jiang, Mianhuan Li, Jie Chen, Yanjie Li, Minghui Yang, Yuchen Gu, Fuxiang Wang, Yuelong Shu, Yang Yang, Litao Sun, Yingxia Liu   +13 more
doaj   +1 more source