Results 11 to 20 of about 12,789,497 (387)

The Axis of Progression of Disease [PDF]

Cancer Informatics, 2014
Starting with genetic or environmental perturbations, disease progression can involve a linear sequence of changes within individual cells. More often, however, a labyrinth of branching consequences emanates from the initial events. How can one repair an entity so fine and so complex that its organization and functions are only partially known?
Tartakoff, Alan M, Wu, Di
openaire   +5 more sources

Facts and Gaps in Exercise Influence on Arrhythmogenic Cardiomyopathy: New Insights From a Meta-Analysis Approach

Frontiers in Cardiovascular Medicine, 2021
Arrhythmogenic cardiomyopathy (ACM) is a genetic cardiac condition characterized by fibrofatty myocardial replacement, either at the right ventricle, at the left ventricle, or with biventricular involvement.
Julia Martínez-Solé, María Sabater-Molina, María Sabater-Molina, María Sabater-Molina, Aitana Braza-Boïls, Aitana Braza-Boïls, Juan J. Santos-Mateo, Pilar Molina, Pilar Molina, Luis Martínez-Dolz, Luis Martínez-Dolz, Juan R. Gimeno, Juan R. Gimeno, Juan R. Gimeno, Esther Zorio, Esther Zorio, Esther Zorio   +16 more
doaj   +1 more source

Risk factors associated with disease progression in a cohort of patients infected with the 2019 novel coronavirus.

Annals of Palliative Medicine, 2020
BACKGROUND The emerging infection of the 2019 novel coronavirus (2019-nCoV) in late December, 2019 in Wuhan, China, has caused an extreme health concern, with many patients having progressed to acute respiratory disease or other complications in a short ...
Yu-Long Zhou, Zhicheng Zhang, Jie Tian, Shaoyun Xiong   +3 more
semanticscholar   +1 more source

Oral Feeding of an Antioxidant Cocktail as a Therapeutic Strategy in a Mouse Model of Rett Syndrome: Merits and Limitations of Long-Term Treatment

Antioxidants, 2022
Rett syndrome (RTT) is a severe neurodevelopmental disorder that typically arises from spontaneous germline mutations in the X-chromosomal methyl-CpG binding protein 2 (MECP2) gene.
Laura Baroncelli, Stefanie Auel, Lena Rinne, Ann-Kathrin Schuster, Victoria Brand, Belinda Kempkes, Katharina Dietrich, Michael Müller   +7 more
doaj   +1 more source

Genome-wide studies in prostate cancer poised liquid biopsy as a molecular discovery tool

Frontiers in Oncology, 2023
Liquid biopsy is emerging as an intriguing tool in clinical disease detection and monitoring. Compared to a standard tissue biopsy, performing a liquid biopsy incurs minimal invasiveness, captures comprehensive disease representation, and can be more ...
Nicholas Lo, Housheng Hansen He, Housheng Hansen He, Sujun Chen, Sujun Chen   +4 more
doaj   +1 more source

Risk factors for disease progression in hospitalized patients with COVID-19: a retrospective cohort study

Infectious Diseases, 2020
Background: To investigate the risk factors related to aggravation and clinical outcomes in coronavirus disease 2019 (COVID-19) patients. Methods: We performed a retrospective study on the risk factors for disease progression of cases with COVID-19 ...
W. Hou, Wei Zhang, R. Jin, Lian-chun Liang, Bin Xu, Zhongjie Hu   +5 more
semanticscholar   +1 more source

Data-Driven Sequence of Changes to Anatomical Brain Connectivity in Sporadic Alzheimer’s Disease

Frontiers in Neurology, 2017
Model-based investigations of transneuronal spreading mechanisms in neurodegenerative diseases relate the pattern of pathology severity to the brain’s connectivity matrix, which reveals information about how pathology propagates through the connectivity ...
Neil P. Oxtoby, Sara Garbarino, Nicholas C. Firth, Nicholas C. Firth, Jason D. Warren, Jonathan M. Schott, Daniel C. Alexander, For the Alzheimer’s Disease Neuroimaging Initiative   +7 more
doaj   +1 more source

Biomarkers of inflammation and repair in kidney disease progression.

Journal of Clinical Investigation, 2020
INTRODUCTION Acute kidney injury and chronic kidney disease (CKD) are common in hospitalized patients. To inform clinical decision-making, more accurate information regarding risk of long-term progression to kidney failure is required.
Jeremy Puthumana, H. Thiessen-Philbrook, Leyuan Xu, S. Coca, A. Garg, J. Himmelfarb, P. Bhatraju, T. Ikizler, E. Siew, L. Ware, Kathleen D. Liu, A. Go, J. Kaufman, P. Kimmel, V. Chinchilli, L. Cantley, C. Parikh   +16 more
semanticscholar   +1 more source

Biomarkers of Disease Progression [PDF]

, 2012
After being informed about a diagnosis of multiple sclerosis (MS), patients are often concerned about the risk of disease progression and future prognosis. Many are naturally concerned over the future course, severity of the disease, and likely disability.
Axel Petzold, Axel Petzold
openaire   +5 more sources

Progression of glomerular diseases [PDF]

Journal of Internal Medicine, 1994
Abstract. The nature and slope of progression of glomerular diseases is the subject of considerable discussion. The use of renal biopsies has been accompanied by considerable improvement in the classification of glomerular disease. However, the clinical and histological tools available to assess prognosis in individual patients lack accuracy ...
E. P. Peten, L. J. Striker
openaire   +3 more sources