Results 51 to 60 of about 12,789,497 (387)

Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis

American Journal of Respiratory and Critical Care Medicine, 2019
Rationale: Idiopathic pulmonary fibrosis (IPF) causes considerable global morbidity and mortality, and its mechanisms of disease progression are poorly understood. Recent observational studies have reported associations between lung dysbiosis, mortality,
D. O’Dwyer, S. Ashley, S. Gurczynski, Meng Xia, C. Wilke, N. Falkowski, Katy C. Norman, K. Arnold, G. Huffnagle, M. Salisbury, M. Han, K. Flaherty, E. White, F. Martinez, J. Erb-Downward, S. Murray, B. Moore, R. Dickson   +17 more
semanticscholar   +1 more source

Recent Progress in Thoracic Disease [PDF]

The Boston Medical and Surgical Journal, 1891
n ...
Sears, George G., Bartol, John W.
openaire   +4 more sources

Progress in Huntington’s disease: the search for markers of disease onset and progression [PDF]

Journal of Neurology, 2015
Unlike most neurodegenerative disorders, individuals at risk from Huntington's disease can be identified prior to the onset of clinical signs of the disease by virtue of it being an autosomal dominant condition. This provides the hypothetical opportunity to delay disease onset and/or slow down the progression of the disease in the very early stages ...
Mason, Sarah, Barker, Roger A
openaire   +3 more sources

The potential for dietary factors to prevent or treat osteoarthritis [PDF]

, 2014
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping, Cassidy, Aedín, Clark, Ian M., Davidson, Rose K., Donell, Simon T., Green, Jonathan A., Hirst-Jones, Kimberley L., Jupp, Orla, Macgregor, Alexander J.   +8 more
core   +1 more source

DNA methylation changes associated with Parkinson’s disease progression: outcomes from the first longitudinal genome-wide methylation analysis in blood

Epigenetics, 2019
Parkinson’s Disease (PD) is a common neurodegenerative disorder currently diagnosed based on the presentation of characteristic movement symptoms. Unfortunately, patients exhibiting these symptoms have already undergone significant dopaminergic neuronal ...
Adrienne Henderson-Smith, Kathleen M. Fisch, Jianping Hua, Ganqiang Liu, Eugenia Ricciardelli, Kristen Jepsen, Mathew Huentelman, Gabriel Stalberg, Steven D. Edland, Clemens R. Scherzer, Travis Dunckley, Paula Desplats   +11 more
doaj   +1 more source

Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET RCT

Health Technology Assessment, 2022
Background: Lung cancer is the leading cause of cancer death. Surgery remains the main method of managing early-stage disease. Minimal-access video-assisted thoracoscopic surgery results in less tissue trauma than open surgery; however, it is not known ...
Eric Lim, Rosie A Harris, Holly E McKeon, Timothy JP Batchelor, Joel Dunning, Michael Shackcloth, Vladimir Anikin, Babu Naidu, Elizabeth Belcher, Mahmoud Loubani, Vipin Zamvar, Lucy Dabner, Timothy Brush, Elizabeth A Stokes, Sarah Wordsworth, Sangeetha Paramasivan, Alba Realpe, Daisy Elliott, Jane Blazeby, Chris A Rogers   +19 more
doaj   +1 more source

Leveraging Disease Progression Learning for Medical Image Recognition

, 2018
Unlike natural images, medical images often have intrinsic characteristics that can be leveraged for neural network learning. For example, images that belong to different stages of a disease may continuously follow a certain progression pattern.
Fevens, Thomas, Lao, Qicheng, Wang, Boyu
core   +1 more source

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

Clinical Cancer Research, 2019
Purpose: The genomic landscape of gliomas has been characterized and now contributes to disease classification, yet the relationship between molecular profile and disease progression and treatment response remain poorly understood.
P. Jonsson, Andrew L. Lin, R. Young, Natalie Distefano, D. Hyman, Bob T. Li, M. Berger, A. Zehir, M. Ladanyi, D. Solit, A. Arnold, Z. Stadler, D. Mandelker, M. Goldberg, J. Chmielecki, Maryam Pourmaleki, Shahiba Q. Ogilvie, S. Chavan, Andrew T. McKeown, Malbora Manne, A. Hyde, K. Beal, T. Yang, C. Nolan, E. Pentsova, A. Omuro, I. Gavrilovic, T. Kaley, E. Diamond, J. Stone, C. Grommes, A. Boire, M. Daras, Anna F Piotrowski, Alexandra M Miller, P. Gutin, T. Chan, V. Tabar, C. Brennan, M. Rosenblum, L. Deangelis, I. Mellinghoff, B. Taylor   +42 more
semanticscholar   +1 more source

Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo [PDF]

, 2020
Significance: Detection and characterization of circulating tumor cells (CTCs), a key determinant of metastasis, are critical for determining risk of disease progression, understanding metastatic pathways, and facilitating early clinical intervention.
Cornelius, Lynn A., Hai, Pengfei, Li, Yang, Qu, Yuan, Shmuylovich, Leonid, Wang, Lihong V., Zhu, Liren   +6 more
core   +1 more source

A dynamic network approach for the study of human phenotypes [PDF]

, 2009
The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases.
A Barrat, A Hinks, A Rzhetsky, AB Begovich, AJ Lusis, Albert-László Barabási, C Benesch, CA Hidalgo, CA Hidalgo, César A. Hidalgo, D Lauderdale, DS Lee, GS Cooper, H Goehler, I Feldman, J Hatten, J Kobberling, J Lim, J Zhang, JB Mitchell, JF Rual, K-I Goh, Lauren Ancel Meyers, LI Iezzoni, MA Pujana, MC Oldham, N Craddock, Nicholas A. Christakis, Nicholas Blumm, P McGuffin, P Wordsworth, S Schneeweiss, SE Ahnert, SE Calvano, SF Grant, U Stelzl   +35 more
core   +5 more sources