Results 11 to 20 of about 828,302 (264)

Environmental epigenomics and disease susceptibility [PDF]

open access: yesNature Reviews Genetics, 2007
Epidemiological evidence increasingly suggests that environmental exposures early in development have a role in susceptibility to disease in later life. In addition, some of these environmental effects seem to be passed on through subsequent generations.
Jirtle, Randy L, Skinner, Michael K
openaire   +3 more sources

Homeostasis, Inflammation, and Disease Susceptibility [PDF]

open access: yesCell, 2015
While modernization has dramatically increased lifespan, it has also witnessed the increasing prevalence of diseases such as obesity, hypertension, and type 2 diabetes. Such chronic, acquired diseases result when normal physiologic control goes awry and may thus be viewed as failures of homeostasis.
Kotas, Maya E., Medzhitov, Ruslan
openaire   +2 more sources

Disturbed Yin–Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1

open access: yesActa Pharmaceutica Sinica B, 2020
Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a lifelong latent infection in the human host. Following primary replication in mucosal epithelial cells, the virus can enter sensory neurons innervating peripheral ...
Chang Yan   +7 more
doaj   +1 more source

Cognitive Reserve as a Protective Factor of Mental Health in Middle-Aged Adults Affected by Chronic Pain

open access: yesFrontiers in Psychology, 2021
Chronic pain is associated with worse mental health and cognitive impairment, which can be a cause or a consequence of brain structure and function alterations, e.g., maladaptive plasticity, antinociceptive system dysregulation.
Selma Delgado-Gallén   +28 more
doaj   +1 more source

Plant Disease Susceptibility Genes? [PDF]

open access: yesThe Plant Cell, 2002
A recent search of the ISI Web of Science identified 524 documents related to “plant disease resistance” and just 1 match for the phrase “plant disease susceptibility.” This does not mean that scientists are not engaged in the study of what makes plants susceptible to disease.
openaire   +2 more sources

Genetic susceptibility to cerebrovascular disease [PDF]

open access: yesCurrent Opinion in Lipidology, 2016
Cerebrovascular disease (CeVD) remains a major cause of death and a leading cause of disability worldwide. CeVD is a complex and multifactorial disease caused by the interaction of vascular risk factors, environment, and genetic factors. In the present article, we discussed genetic susceptibility to CeVD, with particular emphasis on genetic studies of ...
DELLA MORTE, DAVID   +2 more
openaire   +4 more sources

Genetic Predisposition to SARS-CoV-2 Infection: Cytokine Polymorphism and Disease Transmission within Households

open access: yesBiology, 2023
We addressed the question of the influence of the molecular polymorphism of cytokines from different T helper subsets on the susceptibility to SARS-CoV-2 infection. From a cohort of 527 samples (collected from 26 May 2020 to 31 March 2022), we focused on
Marius Saal   +4 more
doaj   +1 more source

Shared 6mer Peptides of Human and Omicron (21K and 21L) at SARS-CoV-2 Mutation Sites

open access: yesAntibodies, 2022
We investigated the short sequences involving Omicron 21K and Omicron 21L variants to reveal any possible molecular mimicry-associated autoimmunity risks and changes in those.
Yekbun Adiguzel, Yehuda Shoenfeld
doaj   +1 more source

Susceptibility to ocular autoimmune disease [PDF]

open access: yesBritish Journal of Ophthalmology, 2000
Editor,—We read with interest the Newsdesk piece in the March 2000 issue of the BJO ,1 commenting on recent studies indicating a conceptual shift …
C E, Egwuagu   +2 more
openaire   +2 more sources

Epigoitrin, an Alkaloid From Isatis indigotica, Reduces H1N1 Infection in Stress-Induced Susceptible Model in vivo and in vitro

open access: yesFrontiers in Pharmacology, 2019
Stress has been proven to modulate an individual’s immune system through the release of pituitary and adrenal hormones such as the catecholamines, growth hormone, and glucocorticoids.
Zhuo Luo   +23 more
doaj   +1 more source

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