Results 21 to 30 of about 875,037 (313)

Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development

open access: yesRedox Biology, 2022
Maternal stress has been associated with poor birth outcomes, including preterm birth, infant mortality, and low birth weight. Bone development disorders in the embryo as a result of maternal stress are believed to be mediated through oxidative stress ...
Jie Niu   +16 more
doaj   +1 more source

Applying multi-omics data to study the genetic background of bovine respiratory disease infection in feedlot crossbred cattle

open access: yesFrontiers in Genetics, 2022
Bovine respiratory disease (BRD) is the most common and costly infectious disease affecting the wellbeing and productivity of beef cattle in North America. BRD is a complex disease whose development is dependent on environmental factors and host genetics.
Jiyuan Li   +6 more
doaj   +1 more source

Disturbed Yin–Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1

open access: yesActa Pharmaceutica Sinica B, 2020
Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a lifelong latent infection in the human host. Following primary replication in mucosal epithelial cells, the virus can enter sensory neurons innervating peripheral ...
Chang Yan   +7 more
doaj   +1 more source

Environmental epigenomics and disease susceptibility [PDF]

open access: yesNature Reviews Genetics, 2007
Epidemiological evidence increasingly suggests that environmental exposures early in development have a role in susceptibility to disease in later life. In addition, some of these environmental effects seem to be passed on through subsequent generations.
Jirtle, Randy L, Skinner, Michael K
openaire   +3 more sources

Cognitive Reserve as a Protective Factor of Mental Health in Middle-Aged Adults Affected by Chronic Pain

open access: yesFrontiers in Psychology, 2021
Chronic pain is associated with worse mental health and cognitive impairment, which can be a cause or a consequence of brain structure and function alterations, e.g., maladaptive plasticity, antinociceptive system dysregulation.
Selma Delgado-Gallén   +28 more
doaj   +1 more source

Genetic Predisposition to SARS-CoV-2 Infection: Cytokine Polymorphism and Disease Transmission within Households

open access: yesBiology, 2023
We addressed the question of the influence of the molecular polymorphism of cytokines from different T helper subsets on the susceptibility to SARS-CoV-2 infection. From a cohort of 527 samples (collected from 26 May 2020 to 31 March 2022), we focused on
Marius Saal   +4 more
doaj   +1 more source

Nativity and Disease Susceptibility [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1929
M,fORTALITY rates from diseases of advanced life in the United States are uniformly higher among the foreign born than among the native born. Furthermore, the mortality rates from these causes are much higher among the Irish and German born than among those born in Italy, Poland and the former Austro-Hungarian empire.
openaire   +2 more sources

Epigoitrin, an Alkaloid From Isatis indigotica, Reduces H1N1 Infection in Stress-Induced Susceptible Model in vivo and in vitro

open access: yesFrontiers in Pharmacology, 2019
Stress has been proven to modulate an individual’s immune system through the release of pituitary and adrenal hormones such as the catecholamines, growth hormone, and glucocorticoids.
Zhuo Luo   +23 more
doaj   +1 more source

Shared 6mer Peptides of Human and Omicron (21K and 21L) at SARS-CoV-2 Mutation Sites

open access: yesAntibodies, 2022
We investigated the short sequences involving Omicron 21K and Omicron 21L variants to reveal any possible molecular mimicry-associated autoimmunity risks and changes in those.
Yekbun Adiguzel, Yehuda Shoenfeld
doaj   +1 more source

Susceptibility to Disease. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1904
Goddard, Kans., Jan. 14, 1904. To the Editor: —I desire to call the attention of the profession to an important factor in the estimation of susceptibility to disease as influenced by age, namely, the decrease in the number of persons living as age increases.
openaire   +2 more sources

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