Results 31 to 40 of about 692,625 (254)

Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?

Frontiers in Cell and Developmental Biology, 2023
Protein tyrosine phosphatases, together with protein tyrosine kinases, control many molecular signaling steps that control life at cellular and organismal levels. Impairing alterations in the genes encoding the involved proteins is expected to profoundly
Wiljan J. A. J. Hendriks, Remco T. P. van Cruchten, Rafael Pulido, Rafael Pulido   +3 more
doaj   +1 more source

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization [PDF]

, 2012
Introduction: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities.
Apel, Maria, Behrens, Frank, Burkhardt, Harald, Böhm, Beate B., Hüffmeier, Ulrike, Reis, André, Uebe, Steffen   +6 more
core   +2 more sources

Tenuazonic Acid-Triggered Cell Death Is the Essential Prerequisite for Alternaria alternata (Fr.) Keissler to Infect Successfully Host Ageratina adenophora

Cells, 2021
The necrotrophic fungus Alternaria alternata contains different pathotypes that produce different mycotoxins. The pathotype Ageratina adenophora secretes the non-host-selective toxin tenuazonic acid (TeA), which can cause necrosis in many plants ...
Jiale Shi, Min Zhang, Liwen Gao, Qian Yang, Hazem M. Kalaji, Sheng Qiang, Reto Jörg Strasser, Shiguo Chen   +7 more
doaj   +1 more source

Interferon lambda protects the female reproductive tract against Zika virus infection [PDF]

, 2019
Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood.
Arora, Nitin, Artyomov, Maxim N., Caine, Elizabeth A., Coyne, Carolyn B., Diamond, Michael S., Moley, Kelle H., Scheaffer, Suzanne M., Zaitsev, Konstantin   +7 more
core   +3 more sources

A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]

, 2012
Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
Baxter, Laura, Bull, James C., Chandler, Dave, Mead, A. (Andrew), Osborne, Juliet L., Pell, Judith K., Prince, Gillian, Ryabov, Eugene V., Zhang, Cunjin   +8 more
core   +4 more sources

Pregnancy and Susceptibility to Infectious Diseases [PDF]

Infectious Diseases in Obstetrics and Gynecology, 2013
To summarize the literature regarding susceptibility of pregnant women to infectious diseases and severity of resulting disease, we conducted a review using a PubMed search and other strategies. Studies were included if they reported information on infection risk or disease outcome in pregnant women. In all, 1454 abstracts were reviewed, and a total of
Elisabeth Sappenfield, Denise J. Jamieson, Athena P. Kourtis   +2 more
openaire   +2 more sources

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy [PDF]

, 1999
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load.
Bangham, C.R.M., Bunce, M., Hall, S.E., Izumo, S., Jeffery, K.J.M., Kodama, D., Lloyd, A.L., Matsumoto, W., Nagai, M., Nowak, M.A., Ogg, G.S., Osame, M., Procter, J., Taylor, G.P., Usuku, K., Weber, J.N., Welsh, K.I.   +16 more
core   +2 more sources

Susceptibility to ocular autoimmune disease [PDF]

British Journal of Ophthalmology, 2000
Editor,—We read with interest the Newsdesk piece in the March 2000 issue of the BJO ,1 commenting on recent studies indicating a conceptual shift …
C E, Egwuagu, P, Charukamnoetkanok, I, Gery   +2 more
openaire   +2 more sources

Cultivar Variation in Hormonal Balance Is a Significant Determinant of Disease Susceptibility to Xanthomonas campestris pv. campestris in Brassica napus

Frontiers in Plant Science, 2017
This study aimed to directly elucidate cultivar variation in disease susceptibility and disease responses in relation to hormonal status in the interaction of Brassica napus cultivars and Xanthomonas campestris pv.
Md. Tabibul Islam, Bok-Rye Lee, Bok-Rye Lee, Sang-Hyun Park, Van Hien La, Dong-Won Bae, Tae-Hwan Kim   +6 more
doaj   +1 more source

Association between GABRG2 Gene Single Nucleotide Polymorphisms and Susceptibility to Ischemic Stroke in a Chinese Population

Journal of Integrative Neuroscience, 2023
Background: Current evidence suggests that Gamma-aminobutyric acid (GABA) receptors are associated with the occurrence and progression of cerebrovascular diseases.
Mingming Ma, Jing Zhao, Dandan Xie, Juan Chen   +3 more
doaj   +1 more source