Results 41 to 50 of about 6,182,453 (264)

Cultivar Variation in Hormonal Balance Is a Significant Determinant of Disease Susceptibility to Xanthomonas campestris pv. campestris in Brassica napus

Frontiers in Plant Science, 2017
This study aimed to directly elucidate cultivar variation in disease susceptibility and disease responses in relation to hormonal status in the interaction of Brassica napus cultivars and Xanthomonas campestris pv.
Md. Tabibul Islam, Bok-Rye Lee, Bok-Rye Lee, Sang-Hyun Park, Van Hien La, Dong-Won Bae, Tae-Hwan Kim   +6 more
doaj   +1 more source

Functional Polymorphisms in the p53 Pathway Genes on the Genetic Susceptibility to Zika Virus Teratogenesis

Frontiers in Cellular and Infection Microbiology, 2021
Congenital Zika Syndrome (CZS) occurs in up to 42% of individuals exposed to ZIKV prenatally. Deregulation in gene expression and protein levels of components of the p53 signaling pathway, such as p53 and MDM2, due to ZIKV infection has been reported ...
Julia A. Gomes, Julia A. Gomes, Julia A. Gomes, Julia A. Gomes, Eduarda Sgarioni, Igor A. Vieira, Igor A. Vieira, Lucas R. Fraga, Lucas R. Fraga, Lucas R. Fraga, Lucas R. Fraga, Patrícia Ashton-Prolla, Patrícia Ashton-Prolla, Ana Cláudia P. Terças-Tretell, Juliana H. da Silva, Bethânia F.R. Ribeiro, Marcial F. Galera, Thalita M. de Oliveira, Maria Denise F. Carvalho de Andrade, Isabella F. Carvalho, Lavínia Schuler-Faccini, Lavínia Schuler-Faccini, Lavínia Schuler-Faccini, Fernanda S. L. Vianna, Fernanda S. L. Vianna, Fernanda S. L. Vianna, Fernanda S. L. Vianna   +26 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Antioxidant and Anti-Inflammatory Properties of Hydrolyzed Royal Jelly Peptide in Human Dermal Fibroblasts: Implications for Skin Health and Care Applications

Bioengineering
Hydrolyzed royal jelly peptide (RJP) has garnered attention for its health-promoting functions. However, the potential applications of RJP in skincare have not been fully explored.
Chang-Yu Yan, Qian-Qian Zhu, Cheng-Xi Guan, Gui-Lan Xiong, Xin-Xing Chen, Hai-Biao Gong, Jia-Wei Li, Shu-Hua Ouyang, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He   +10 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. [PDF]

, 2009
Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been
Weber, Bernhard H. F., Fleckenstein, Monika, Frank G Holz, Weber, B. H., Hendrik P N Scholl, Scholl, Hendrik P. N., Tim Becker, Ulrich Mansmann, Weinberger Andreas W. A., Schmitz-Valckenberg Steffen, Mackensen, F., Herold Christine, Holz, Frank G, Scholl Hendrik P. N., Weber, Bernhard H F, Andreas Mössner, Keilhauer, Claudia N, Scholl, Hendrik P N, Fritsche, Lars G., Steffen Schmitz-Valckenberg, Schmitz-Valckenberg, S., Claudia N Keilhauer, Weinberger, A. W., Fritsche, Lars G, Weinberger, Andreas W. A., Pauleikhoff, D., Becker, T., Andreas W A Weinberger, Adrion, Christine, Mansmann Ulrich, Weber Bernhard H. F., Becker Tim, Göbel, Arno, Mackensen Friederike, Holz, F. G., Monika Fleckenstein, Göbel, A., Adrion Christine, Holz Frank G., Scholl, H. P., Friederike Mackensen, Mackensen, Friederike, Mansmann, Ulrich, Göbel Arno, Becker, Tim, Fleckenstein Monika, Mössner, Andreas, Lars G Fritsche, Fritsche Lars G., Keilhauer Claudia N., Schmitz-Valckenberg, Steffen, Fritsche, L. G., Herold, Christine, Arno Göbel, Daniel Pauleikhoff, Weinberger, Andreas, Christine Herold, Mansmann, U., Christine Adrion, Bernhard H F Weber, Mössner, A., Pauleikhoff, Daniel, Keilhauer, C. N., Herold, C., Holz, Frank G., Adrion, C., Mößner Andreas, Pauleikhoff Daniel, Fleckenstein, M.   +68 more
core   +2 more sources

Hepatic microcirculatory disturbance in liver diseases: intervention with traditional Chinese medicine

Frontiers in Pharmacology
The liver, a complex parenchymal organ, possesses a distinctive microcirculatory system crucial for its physiological functions. An intricate interplay exists between hepatic microcirculatory disturbance and the manifestation of pathological features in ...
Pei Liu, Pei Liu, Wan-Li Liang, Wan-Li Liang, Rui-Ting Huang, Rui-Ting Huang, Xin-Xing Chen, De-Hua Zou, De-Hua Zou, Hiroshi Kurihara, Yi-Fang Li, You-Hua Xu, Shu-Hua Ouyang, Rong-Rong He, Rong-Rong He   +14 more
doaj   +1 more source

From Genetics to Epigenetics, Roles of Epigenetics in Inflammatory Bowel Disease

Frontiers in Genetics, 2019
Inflammatory bowel disease (IBD) is a destructive, recurrent, and heterogeneous disease. Its detailed pathogenesis is still unclear, although available evidence supports that IBD is caused by a complex interplay between genetic predispositions ...
Zhen Zeng, Zhen Zeng, Arjudeb Mukherjee, Hu Zhang, Hu Zhang   +4 more
doaj   +1 more source

Comprehensive Statistical and Bioinformatics Analysis in the Deciphering of Putative Mechanisms by Which Lipid-Associated GWAS Loci Contribute to Coronary Artery Disease

Biomedicines, 2022
The study was designed to evaluate putative mechanisms by which lipid-associated loci identified by genome-wide association studies (GWAS) are involved in the molecular pathogenesis of coronary artery disease (CAD) using a comprehensive statistical and ...
Victor Lazarenko, Mikhail Churilin, Iuliia Azarova, Elena Klyosova, Marina Bykanova, Natalia Ob'edkova, Mikhail Churnosov, Olga Bushueva, Galina Mal, Sergey Povetkin, Stanislav Kononov, Yulia Luneva, Sergey Zhabin, Anna Polonikova, Alina Gavrilenko, Igor Saraev, Maria Solodilova, Alexey Polonikov   +17 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source