Results 61 to 70 of about 692,625 (254)

Regulation and Functions of ROP GTPases in Plant–Microbe Interactions

Cells, 2020
Rho proteins of plants (ROPs) form a specific clade of Rho GTPases, which are involved in either plant immunity or susceptibility to diseases. They are intensively studied in grass host plants, in which ROPs are signaling hubs downstream of both cell ...
Stefan Engelhardt, Adriana Trutzenberg, Ralph Hückelhoven   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Adaptability of safflower (Carthamus tinctorius L.) genotypes to some New Zealand environments : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Plant Science at Massey University [PDF]

, 1981
Seven safflower (Carthamus tinctorius L.) genotypes were grown at three sites (Massey, Aorangi and Flockhouse) in the Manawatu area in years 1978 and 1979. Three additional genotypes from the world germplasm collection were included in the study in 1979.
De Silva, Handunnethi Nihal
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Predicting the size and probability of epidemics in a population with heterogeneous infectiousness and susceptibility [PDF]

, 2007
We analytically address disease outbreaks in large, random networks with heterogeneous infectivity and susceptibility. The transmissibility $T_{uv}$ (the probability that infection of $u$ causes infection of $v$) depends on the infectivity of $u$ and the
G. Chowell, H. S. Wilf, Joel C. Miller, L. A. Meyers, M. Molloy, P. Grassberger, R. M. Anderson, R. R. Kao   +7 more
core   +1 more source

Environmental epigenomics and disease susceptibility [PDF]

EMBO reports, 2011
The Keystone symposium on ‘Environmental Epigenomics and Disease Susceptibility’ was held in late March 2011 at the Grove Park Inn Resort in Asheville, North Carolina, USA. The meeting helped to define the developing field of ‘environmental epigenetics’ and the research presented established its role in disease aetiology and susceptibility.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

CISH and Susceptibility to Infectious Diseases [PDF]

New England Journal of Medicine, 2010
The interleukin-2-mediated immune response is critical for host defense against infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a suppressor of cytokine signaling, controls interleukin-2 signaling.Using a case-control design, we tested for an association between CISH polymorphisms and susceptibility to major ...
Khor, C.C., Vannberg, F.O., Chapman, S.J., Guo, H., Wong, S.H., Walley, A.J., Vukcevic, D., Rautanen, A., Mills, T.C., Chang, K.-C., Kam, K.-M., Crampin, A.C., Ngwira, B., Leung, C.-C., Tam, C.-M., Chan, C.-Y., Sung, J.J.Y., Yew, W.-W., Toh, K.-Y., Tay, S.K.H., Kwiatkowski, D., Lienhardt, C., Hien, T.-T., Day, N.P., Peshu, N., Marsh, K., Maitland, K., Scott, J.A., Williams, T.N., Berkley, J.A., Floyd, S., Tang, N.L.S., Fine, P.E.M., Goh, D.L.M., Hil, A.V.S.   +34 more
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources