Results 71 to 80 of about 6,182,453 (264)

The role of host PrP in Transmissible Spongiform Encephalopathies [PDF]

, 2007
PrP has a central role in the Transmissible Spongiform Encephalopathies (TSEs), and mutations and polymorphisms in host PrP can profoundly alter the host's susceptibility to a TSE agent.
Barron, Rona M, Wiseman, Frances, Barron, Rona, Hart, Patricia, Manson, Jean C., Wiseman, Patricia, Cancellotti, Enrico, Bishop, Matthew T., Barron, Rona M., Bishop, Matthew T, Manson, Jean C   +10 more
core   +1 more source

Differential plague susceptibility in species and populations of prairie dogs

Ecology and Evolution, 2019
Laboratory trials conducted over the past decade at U.S. Geological Survey National Wildlife Health Center indicate that wild populations of prairie dogs (Cynomys spp.) display different degrees of susceptibility to experimental challenge with fully ...
Robin E. Russell, Daniel W. Tripp, Tonie E. Rocke   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Susceptibility to Phytophthora ramorum in a key infectious host: Landscape variation in host genotype, host phenotype, and environmental factors [PDF]

, 2008
• Sudden oak death is an emerging forest disease caused by the invasive pathogen Phytophthora ramorum. Genetic and environmental factors affecting susceptibility to P.
Hüberli, D., Gordon, S., Rank, N.E., Harnik, T.Y., Garbelotto, M., Anacker, B.L., Meentemeyer, R., Whitkus, R.   +7 more
core  

Promoter variants in tissue inhibitor of metalloproteinase-3 (TIMP-3) protect against susceptibility in pigeon breeders' disease. [PDF]

, 2004
BACKGROUND: Tissue inhibitors of metalloproteinases (TIMPs) play a major role in extracellular matrix turnover in the lung. However, in chronic lung disorders such as idiopathic pulmonary fibrosis (IPF) and pigeon breeders' disease (PBD), TIMPs may ...
Briggs, L, Montaño, MM, Pardo, A, Estrada, A, Laurent, GJ, Selman, M, Hill, MR, Pardo-Cemo, Annie   +7 more
core   +1 more source

Contribution of miR-124 rs531564 polymorphism to the occurrence of congenital Zika syndrome

Epigenetics, 2023
Zika virus (ZIKV) cause Congenital Zika Syndrome (CZS) in individuals exposed during pregnancy. Studies have shown that ZIKV infection positively regulates the miR-124 expression in neural cells, which leads to a decrease of TFRC, a gene targeted of this
Julia A Gomes, Igor Araujo Vieira, Eduarda Sgarioni, Ana Cláudia P Terças-Tretell, Juliana H da Silva, Bethânia FR Ribeiro, Marcial F Galera, Thalita M de Oliveira, Maria Denise F Carvalho de Andrade, Isabella F Carvalho, Lavínia Schüler-Faccini, Fernanda SL Vianna   +11 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Cultivar and Training System Impact Cold-climate Seedless Table Grape Performance in the Northeastern United States

HortScience
We grew eight cultivars of seedless table grape in Durham, NH, USA, from 2015 to 2021, using two training systems: Munson and vertical shoot positioning (VSP).
Rebecca Grube Sideman, George Hamilton, Kaitlyn Orde   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Genetics of animal health and disease in cattle [PDF]

, 2011
peer-reviewedThere have been considerable recent advancements in animal breeding and genetics relevant to disease control in cattle, which can now be utilised as part of an overall programme for improved cattle health.
Bermingham Mairead L, Margaret Good, Berry, D.P., More Simon J, Bermingham, M.L., Berry Donagh P, Berry, Donagh P., Good, Margaret, Good Margaret, Donagh P Berry, Bermingham, Mairead L, Good, M., More, S.J., Bermingham, Mairead L., More, Simon J, Simon J More, Mairead L Bermingham, et al., Berry, Donagh   +18 more
core   +1 more source