Results 11 to 20 of about 151,600 (219)
In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury
HemaSphere, 2023 Drug repurposing is a valuable strategy for rare diseases. Sickle cell disease (SCD) is a rare hereditary hemolytic anemia accompanied by acute and chronic painful episodes, most often in the context of vaso-occlusive crisis (VOC).
Enrica Federti +20 more
doaj +1 more source
Східноукраїнський медичний журнал, 2020 The article presents an optimized model of medical care for the population with diseases of the blood and blood-forming organs at the regional level in modern conditions of health care reform based on the current legislation of Ukraine on health care ...
V. V. Horokh
doaj +1 more source
From Genotype to Phenotype: How Enhancers Control Gene Expression and Cell Identity in Hematopoiesis
HemaSphere, 2023 Blood comprises a wide array of specialized cells, all of which share the same genetic information and ultimately derive from the same precursor, the hematopoietic stem cell (HSC).
Roger Mulet-Lazaro, Ruud Delwel
doaj +1 more source
A Question of Frame: The Role of the Bone Marrow Stromal Niche in Myeloid Malignancies
HemaSphere, 2023 Until a few years ago, the onset of acute myeloid leukemia (AML) was entirely ascribed to genetic lesions in hematopoietic stem cells. These mutations generate leukemic stem cells, which are known to be the main ones responsible for chemoresistance and ...
Chiara Tomasoni +4 more
doaj +1 more source
Impact of SARS-CoV-2 infection on patients with hematological malignancies: a retrospective study
Hematology, 2023 Objectives This study aimed to evaluate the characteristics of patients with hematological malignancies (HM) and SARS-CoV-2 infection and analyze the risk factors of their severity and mortality.Methods A retrospective study including inpatients ...
Huihan Zhao +5 more
doaj +1 more source
Adult Incidence in the Russian European Arctic with Developed Mining and Metallurgical Industry (en)
Российская Арктика, 2019 The purpose of the research. The research aims to assess the adult incidence within the mining complex in the Murmansk Region (the Russian Arctic). Materials and methods.
A. N. Nikanov +4 more
doaj +1 more source
Diseases of the poultry reproductive organs (Case study: Altai Region, Russia) [PDF]
Caspian Journal of Environmental SciencesWe carried out a complex research on the determination of pathogenesis and etiology of diseases of egg-forming organs in laying hens in conditions of industrial breeding.
Sergey V. Fedotov +2 more
doaj +1 more source
IgG4 Subclass of Immunoglobulins; Immunobiology and Roles in Relation to Human Diseases
Acta MedicaIgG4, a subclass of antibodies known as immunoglobulins have unique structural features, in particular, their Fc regions, that prevents their interactions with other receptors on effector cells and thus disabling them of activating complements system ...
Eva Malá, Moeina Afshari, Jan Krejsek
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source