Results 21 to 30 of about 139,722 (205)

IgG4 Subclass of Immunoglobulins; Immunobiology and Roles in Relation to Human Diseases

Acta Medica
IgG4, a subclass of antibodies known as immunoglobulins have unique structural features, in particular, their Fc regions, that prevents their interactions with other receptors on effector cells and thus disabling them of activating complements system ...
Eva Malá, Moeina Afshari, Jan Krejsek
doaj   +1 more source

Translation and cultural adaptation of the Health Utilities Preschool to Brazilian Portuguese

Hematology, Transfusion and Cell Therapy
Introduction: Health research is particularly important in low- and middle-income countries (LMICs), where improvements must be achieved with limited resources, and where the great majority of the world's population, especially children, live ...
Karina Viani, Bruno Fernandes Bernardes, Marilia Nasz Veiga, Renato Canton Viani, Tomas Marzagão Barbuto, Ronald D. Barr   +5 more
doaj   +1 more source

High PD-L1 expression is associated with unfavorable clinical features in myelodysplastic neoplasms

Hematology, Transfusion and Cell Therapy
Abstatct: Introduction: Immune checkpoints are regulators of the immune system response that allow self-tolerance. Molecules such as Programmed Cell Death Protein 1 (PD-1) and its Ligand (PD-L1) participate in the immune checkpoint by signaling co ...
Leticia Rodrigues Sampaio, Mateus de Aguiar Viana, Vanessa Silva de Oliveira, Bruna Vitoriano Ferreira, Mayara Magna Lima Melo, Roberta Taiane Germano de Oliveira, Daniela de Paula Borges, Silvia Maria Meira Magalhãesa, Ronald F. Pinheiro   +8 more
doaj   +1 more source

THE RELATION OF THE SPLEEN TO BLOOD DESTRUCTION AND REGENERATION AND TO HEMOLYTIC JAUNDICE

Journal of Experimental Medicine, 1915
These experiments indicate, therefore, that when hemoglobin is set free in the portal circulation a larger amount is held by the liver and converted rapidly into bile pigment than is the case when it is set free in the general circulation, and that ...
Xil The I M P O R T A N C E In T H E Production Of H E, J. H. Austin, O. H. Perry Pepper   +2 more
semanticscholar   +1 more source

Factores de riesgo cardiovascular y su relación con la progresión de la enfermedad venosa crónica

Revista Mexicana de Angiología
Antecedentes: La progresión de la enfermedad venosa crónica (EVC) suele estar ligada a factores de riesgo que son motivo de investigación aun sin asociación clara.
Leopoldo E. Padilla-Hernández, Omar A. Hernández-Hurtado, Carlos Flores-Ramírez, Joaquín M. Santoscoy-Ibarra, Luis B. Enríquez-Sánchez, Raúl A. Hinojos-Flotte, Dalia G. Delgado-Ortega, Yarazi M. Carrasco-Arredondo   +7 more
doaj   +1 more source

Tumor lysis syndrome in hematological inpatients, experience from a university hospital in Brazil: A retrospective cohort study

Hematology, Transfusion and Cell Therapy
Introduction: The tumor lysis syndrome is a medical emergency. Its presentation can be spontaneous or secondary, as a consequence of the established treatment. The diagnosis and treatment of the tumor lysis syndrome (TLS) has become a crucial goal to the
Ebellins Tabares Calvache, Allison Dessiret Tabares Calvache, Cristiane Seganfredo Weber   +2 more
doaj   +1 more source

Progress in the clinical effects and adverse reactions of ticagrelor

Thrombosis Journal
Background Ticagrelor is a novel receptor antagonist that selectively binds to the P2Y12 receptor, thereby inhibiting adenosine diphosphate (ADP)-mediated platelet aggregation.
Peng Wei, Xiaoqing Wang, Qiang Fu, Bangming Cao   +3 more
doaj   +1 more source

IL-4Rα (rs1801275) A>G polymorphism in Egyptian immune thrombocytopenia (ITP) patients: a single center experience

Hematology, Transfusion and Cell Therapy
Introduction: Chronic immune thrombocytopenia (cITP) is characterized by dysregulation of the immune response. Until recently, the role of Th2-related cytokine gene polymorphisms was unclear.
Mohamed Abdelkader Morad, Noha A. Doudar, Nehad Tawfeek, Maha Yacoub, Taha Azoz, Doaa El Demerdash   +5 more
doaj   +1 more source

Human leukocyte antigen immunization in transfusion-dependent Moroccan patients with beta-thalassemia major: prevalence and risk factors

Hematology, Transfusion and Cell Therapy
Introduction: Beta-thalassemia major patients need a regular blood transfusion to have an initial normal growth. However, these patients have an increased risk of developing alloantibodies. Our main goal was to study HLA alloimmunization in Moroccan Beta-
Sanae Ouadghiri, Kaoutar El Morabit, Naoual Elansari, Ouafae Atouf, Maria Elkababri, Laila Hessissen, Malika Essakalli   +6 more
doaj   +1 more source

ABO blood group discrepancies in blood donor and patient samples at a tertiary care oncology centre: analysis and serological resolution

Hematology, Transfusion and Cell Therapy
Introduction: In serological testing, determination of ABO grouping requires both antigen typing for A and B antigens and screening of serum or plasma for A and B antibodies.
Priti Desai, Anisha Navkudkar, Sunil Rajadhyaksha   +2 more
doaj   +1 more source