Results 91 to 100 of about 137,095 (246)

EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer

Journal of Experimental & Clinical Cancer Research
Background Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide, and treatment options for advanced CRC are limited. The regulatory mechanisms of aberrant NAT10-mediated N4-acetylcytidine (ac4C) modifications in cancer ...
Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An   +12 more
doaj   +1 more source

Meeting update: faecal microbiota transplantation––bench, bedside, courtroom? [PDF]

, 2016
A group of stakeholders met, under the aegis of the British Society of Gastroenterology, to discuss the current landscape of faecal microbiota transplant- ation (FMT) within the UK and beyond.
Ding, N, Hart, A, Marchesi, J, McLaughlin, J, Mullish, BH   +4 more
core   +1 more source

Essential Updates 2023/2024: Recent Advances of Multimodal Approach in Patients for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Gastric cancer remains a major global health burden, especially in East Asia. Recent years have brought significant advances in multimodal management, including surgery, perioperative chemotherapy, immunotherapy, and supportive care. This review summarizes key updates from 2023 to 2024, focusing on surgical innovations, perioperative systemic ...
Katsutoshi Shoda, Yoshihiko Kawaguchi, Suguru Maruyama, Daisuke Ichikawa   +3 more
wiley   +1 more source

Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]

, 2016
Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core   +2 more sources

Impact of Ghrelin‐Depleting Gastrectomy on Long‐Term Endocrine and Metabolic Health With a Focus on Skeletal Muscle and Bone Mineral Content

Annals of Gastroenterological Surgery, EarlyView.
This study investigates the long‐term endocrine and metabolic consequences of ghrelin‐depleted gastrectomy, with a focus on skeletal muscle mass and bone mineral content. Sustained reductions in serum desacyl‐ghrelin were linked to lower IGF‐1 levels, resulting in significant loss of muscle and bone.
Hiroki Harada, Takuya Goto, Keishi Yamashita, Hiroyuki Minoura, Kota Okuno, Shohei Fujita, Mikiko Sakuraya, Tadashi Higuchi, Koshi Kumagai, Naoki Hiki   +9 more
wiley   +1 more source

Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. [PDF]

, 2013
Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), graft-versus-host disease (GVHD), and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are common human gastrointestinal diseases that share inflammation as a key
Bortner, James D, Falk, Gary W, Hartman, Kira G, Lynch, John P, Martín, Martín G, Rustgi, Anil K, Yu, Jian   +6 more
core   +2 more sources

Patient‐Reported Outcomes and Surgical Results of Hand‐Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4–5 cm From the Anal Verge: A Subanalysis of the Ultimate Study

Annals of Gastroenterological Surgery, EarlyView.
Preserving anorectal function while ensuring oncological success is critical in lower rectal cancer surgery. This multicenter prospective study compared hand‐sewn and stapled anastomosis in 135 patients with tumors 4–5 cm from the anal verge. Although post‐operative complications and oncological outcomes were similar, stapled anastomosis consistently ...
Masakatsu Numata, Jun Watanabe, Yuichiro Tsukada, Yusuke Suwa, Yosuke Fukunaga, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Masanori Yoshimitsu, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Takeshi Naitoh, Masahiko Watanabe, Motoko Suzuki, Toshihiro Misumi, Masaaki Ito, Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery   +29 more
wiley   +1 more source

Health related effects of wheat varieties [PDF]

, 2020
Summarises the different effects wheat digestion has on human ...
Borgen, Anders
core  

Immediate Reconstruction of Pancretaticogastrostomy Following Hepatopancreatoduodenectomy for Biliary Tact Cancer: A Single‐Center Review of 33 Consecutive Patients

Annals of Gastroenterological Surgery, EarlyView.
This study showed that the pancreaticogastrostomy technique in HPD of biliary tract cancer reduced the incidence of pancreatic fistula from 45% to 12%. In‐hospital mortality was also reduced from 27% to 3%. ABSTRACT Background and Purpose Although hepatopancreaticoduodenectomy (HPD) is effective for margin‐negative curative resection of biliary tract ...
Ryusei Matsuyama, Yasuhiro Yabusita, Tomoaki Takahashi, Yutaro Kikuchi, Kouta Sahara, Kentaro Miyake, Yu Sawada, Yuuki Homma, Takafumi Kumamoto, Itaru Endo   +9 more
wiley   +1 more source

CD47: an immunoregulatory nexus in liver and gastrointestinal disorders

eGastroenterology
Cluster of differentiation 47 (CD47) is a widely expressed transmembrane protein that serves as a critical immunoregulatory checkpoint in both homeostatic and pathological conditions of the digestive system.
Shuxia Wang, Josephine Otuagomah, Alana Newcomb, Taesik Gwag   +3 more
doaj   +1 more source