Results 71 to 80 of about 106,055 (260)

ASGE guideline for endoscopic full-thickness resection and submucosal tunnel endoscopic resection

VideoGIE, 2019
With the development of reliable endoscopic closure techniques and tools, endoscopic full-thickness resection (EFTR) is emerging as a therapeutic option for the treatment of subepithelial tumors and epithelial neoplasia with significant fibrosis.
Harry R. Aslanian, MD, FASGE, Amrita Sethi, MD, FASGE, Manoop S. Bhutani, MD, FASGE, Adam J. Goodman, MD, FASGE, Kumar Krishnan, MD, David R. Lichtenstein, MD, FASGE, Joshua Melson, MD, FASGE, Udayakumar Navaneethan, MD, Rahul Pannala, MD, MPH, FASGE, Mansour A. Parsi, MD, MPH, FASGE, Allison R. Schulman, MD, MPH, Shelby A. Sullivan, MD, Nirav Thosani, MD, Guru Trikudanathan, MBBS, MD, Arvind J. Trindade, MD, Rabindra R. Watson, MD, John T. Maple, DO, FASGE   +16 more
doaj   +1 more source

Microbial changes from bariatric surgery alters glucose-dependent insulinotropic polypeptide and prevents fatty liver disease

Gut Microbes, 2023
Bariatric surgery remains a potent therapy for nonalcoholic fatty liver disease (NAFLD), but its inherent risk and eligibility requirement limit its adoption.
Tien S. Dong, William Katzka, Julianne C. Yang, Candace Chang, Nerea Arias-Jayo, Venu Lagishetty, Anna Balioukova, Yijun Chen, Erik Dutson, Zhaoping Li, Emeran A. Mayer, Joseph R. Pisegna, Claudia Sanmiguel, Jonathan P. Jacobs   +13 more
doaj   +1 more source

Nutrition, the digestive system and immunity in COVID-19 infection [PDF]

, 2020
The current review aimed to synthesize the literature on the complex relationship between food consumption and nutritional status as well as the digestive system in order to examine the relationship between immunity and potential responses to COVID-19 ...
Harris, Miranda, Bold, Justine, Chouchane, M., Fellows, Lindsey   +3 more
core  

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source

Intraepithelial lymphocytes, scores, mimickers and challenges in diagnosing gluten-sensitive enteropathy (celiac disease)

, 2017
The upper digestive tract is routinely scoped for several causes of malabsorption, and the number of duodenal biopsy specimens has increased notably in the last 10 years.
Shen, Fan, Bouma, Gerd, Sergi, Consolato
core   +1 more source

Effect of Lactulose on the Intestinal Flora of Elderly Constipation Patients With Chronic Renal Insufficiency

AGING MEDICINE, EarlyView.
This study investigates the regulatory effects of lactulose and polyethylene glycol (PEG) on the composition of gut microbiota in elderly constipation patients with chronic renal insufficiency by comparing the changes in microbial abundance. Both lactulose and PEG significantly modulate the gut microbiota structure, though their specific mechanisms and
Jianxia Ma, Jun Wang, Tianran Han, Zhifang Shao, Weiqi Zhang, Ke Wang, Qinlian Zeng, Kangwei Liu, Yuanwen Chen, Songbai Zhen, Jianfeng Yao   +10 more
wiley   +1 more source

A greener gastroenterology: challenges and opportunities for an eco-sustainable approach to digestive diseases

Gastroenterology as a specialty can make a substantial contribution to reducing the carbon footprint of the health-care system. Concrete actions are needed to increase awareness, education and evidence-based knowledge on eco-sustainable diagnostic and ...
Cammarota G., Ianiro G.
core   +1 more source

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Pylorus‐Preserving Gastrectomy for Gastric Cancer: Current Evidence and Future Directions

Annals of Gastroenterological Surgery, EarlyView.
This review aims to outline the current evidence and future directions of PPG, focusing on the feasibility of extending its application beyond its traditional indications. ABSTRACT Pylorus‐preserving gastrectomy (PPG) is a function‐preserving surgery for clinically T1N0M0 (cT1N0M0) early gastric cancer (EGC) located in the middle third of the stomach ...
Sa‐Hong Kim, Hyuk‐Joon Lee
wiley   +1 more source