Results 131 to 140 of about 106,055 (260)

Considerations on the Quality of Clinical Trials on Non-alcoholic Fatty Liver Disease

, 2016
Non-alcoholic fatty liver disease (NAFLD) become the focus of health concern due to the liver injury it caused and a series of metabolic disorders it brought.
Ji, Guang; Institute of Digestive Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine,, Zhang, Li; Institute of Digestive Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine   +1 more
core  

Outcomes of surgical versus conservative treatment in pediatric median arcuate ligament syndrome

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Median arcuate ligament syndrome (MALS) involves compression of the celiac artery and presents with gastrointestinal symptoms. We evaluated outcomes after surgical versus conservative management in pediatric MALS. Methods We reviewed charts of symptomatic patients aged 7–21 years diagnosed by ultrasound and/or computed tomography ...
Mohamad Abi Nassif, Juan Gurria, Danny Mallon, Rashmi Sahay, Lev Dorfman, Emily Vore, Jennifer Hardy, Kaitlin Whaley, Alex Nasr, Neha R. Santucci   +9 more
wiley   +1 more source

Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis

JPGN Reports, EarlyView.
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley   +1 more source

Gut function among children treated for severe acute malnutrition: A cohort study in Uganda

JPGN Reports, EarlyView.
Abstract Objectives Impaired gut function in children with severe acute malnutrition (SAM) is associated with morbidity. We aimed to assess changes in six biomarkers representing different domains of gut function among children with complicated SAM during nutritional rehabilitation, and to identify predictors of these changes.
Betty Lanyero, Nicolette Nabukeera–Barungi, Ezekiel Mupere, Bikila S. Megersa, Iris Weidema, Pingping Jiang, Maria Wiese, Musemma K. Muhammed, Henrik Friis, Hanne Frøkiær, Dennis S. Nielsen, Vibeke Brix Christensen, Benedikte Grenov   +12 more
wiley   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu, Chien‐Ming Chen, Tony Kou, Tai‐Di Chen, Ming‐Jung Meng, Chen‐Wang Chang, Jen‐Wei Chou, Tien‐Yu Huang, Cheng‐Tang Chiu, Yu‐Bin Pan, Puo‐Hsien Le, Ming‐Yao Su   +11 more
wiley   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

easyGBDR: An Integrated R Toolkit for Comprehensive Secondary Analysis of Global Burden of Disease Database

Med Research, EarlyView.
ABSTRACT The Global Burden of Disease (GBD) database provides essential primary data for public health research. However, its complexity and diversity pose challenges for conducting advanced secondary analyses. To address these challenges, we developed easyGBDR, an innovative integrated R toolkit designed to facilitate the secondary analysis of GBD ...
Yingying Fang, Zeyu Li, Yiming Song, Xiaolu Lin, Xiaojie Huang, Kang Wang, Quan Gan, Xu Zhang, Qingwei Zhang, Xiaobo Li   +9 more
wiley   +1 more source

Development and Validation of a Questionnaire‐Based Model for Households With Multiple Helicobacter pylori Infections: A Family‐Based Screening Strategy

Med Research, EarlyView.
This study developed and externally validated a questionnaire‐based household risk model to identify families with multiple Helicobacter pylori infections. Using only noninvasive, readily available household information, the model showed good discrimination and enabled a family‐based screening strategy that substantially improved detection efficiency ...
Yifan Qiu, Xianzhu Zhou, Yi Hu, Liting Shen, Jiayue Wang, Shihan Xu, Huiyun Zhu, Huabing Huang, Zhaoshen Li, Yiqi Du   +9 more
wiley   +1 more source

Large language model chatbot-based text-to-SQL application for database analyses in liver diseases and hepatology research. [PDF]

JAMIA Open
Far AT, Sun S, Jutras G, Wang MB, Burns S, Owens J, Galvez V, Somsouk M, Lai JC, Lai K, Ge J.   +10 more
europepmc   +1 more source