Results 51 to 60 of about 454,454 (320)

Diseases of the digestive system

Kazan medical journal, 1934
In the preface to his book, Prof. R.A. Luria writes: "Diseases of the digestive organs are undoubtedly the most frequent diseases with which the therapist has to deal. It is impossible not to agree with this, as well as with the idea that this area of internal medicine is the least familiar to a wide range of physicians.
openaire   +2 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Computer Aided Diagnosis System for Wireless Capsule Endoscopy Video [PDF]

, 2011
Along with the advancing of technology in wireless and miniature camera, Wireless Capsule Endoscopy (WCE), the combination of both, enables a physician to diagnose patient's digestive system without actually perform a surgical procedure.
Chen, Ying-ju, Lee, Jeongkyu
core  

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks. [PDF]

, 2018
Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability.
Chen, Hongping, Choi, Eric T., Cueto, Ramon, Drosatos, Konstantinos, Fu, Hangfei, Nanayakkara, Gayani K, Park, Joon Y., Qin, Xuebin, Shao, Lijian, Shao, Ying, Sheng, Haitao, Sun, Jianxin, Sun, Yu, Wang, Hong, Wang, Luqiao, Wu, Na, Yang, Qian, Yang, William Y, Yang, Wuping, Yang, Xiaofeng, Zeng, Huihong, Zhu, Qingxian   +21 more
core   +2 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Common molecular basis for MASH and hepatitis C revealed via systems biology approach

Frontiers in Oncology
BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is characterized by liver inflammation and damage caused by a buildup of fat in the liver.
Yongwei Cheng, Zihao Song, Ye Liu, Xichao Xu, Dali Zhang, Yigui Zou, Liang Liu, Yinzhen Zeng, Wenwen Li, Daming Bai, Dongling Dai   +10 more
doaj   +1 more source

The Cost of Care: New Insights into Healthcare Spending Growth [PDF]

, 2017
[Excerpt] The Bureau of Labor Statistics (BLS) is celebrating the first anniversary of experimental disease-based price indexes, which adjust expenditures on disease for inflation.
Bradley, Ralph
core   +1 more source

Multimorbidity as an important issue among women: results of gender difference investigation in a large population-based cross-sectional study in West Asia [PDF]

, 2017
Objectives: To investigate the impact of gender on multimorbidity in northern Iran. Design: A cross-sectional analysis of the Golestan cohort data. Setting: Golestan Province, Iran.
Akbar Feyz-Sani, Akram Pourshams, Alireza Delavari, Alireza Sadjadi, Amir Mahdi Sadjadi, Azam Majidi, Batoul Ahmadi, Christian C Abnet, Farhad Islami, Farin Kamangar, Hossein Poustchi, Masoomeh Alimohammadian, Masoud Khoshnia, Mehdi Yaseri, Mohammad Amani, Mohammad Derakhshan, Paolo Boffetta, Paul Brennan, Reza Malekzadeh, Samad Qaravi, Sanford Dawsey   +20 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms

Frontiers in Pharmacology
Dachengqi decoction (DCQD) is a traditional Chinese medicine formula consisting of three botanical drugs and one mineral drug. It has anti-inflammatory, gastrointestinal motility, and microcirculation improvement effects.
Wen Guo, Wen Guo, Xiaobin Zhang, Xiaobin Zhang, Xin Zhou, Xin Zhou, Wangpeng Lan, Wangpeng Lan, Jianqin Liu, Yali Liu, Yali Liu, Li Li, Li Li, Zhi Li, Zhi Li, Zhi Li   +15 more
doaj   +1 more source